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920-106 exam Dumps Source : NNCSS SYMPOSIUM convene CENTER

Test Code : 920-106
Test cognomen : NNCSS SYMPOSIUM convene CENTER
Vendor cognomen : Nortel
: 90 real Questions

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Nortel NNCSS SYMPOSIUM convene CENTER

VoIP certification tracks - Nortel's support certifications | killexams.com real Questions and Pass4sure dumps

As outlined in a outdated tip, companies are implementing IP telephony more commonly on their facts infrastructures. The accelerated deployment has created a necessity for certified IP telephony engineers to deliver proven, most beneficial-of-breed expertise.

The IP telephony certifications Nortel at present presents are divided into four classes: steer specialist, Design expert, support skilled, and Design skilled. This tip discusses the Nortel support music.

assist specialist

The steer professional certifications are intended to demonstrate an individual's means to Put into effect, operate, and troubleshoot a Nortel Networks IP Telephony answer. The support expert certification reflects a candidate with three to six months of event that can deal with pursuits technical issues of a common Nortel IP Telephony answer.

NNCSS - VoIP Succession BCM 3.0

This certification checks the skill to Put into effect, function, and troubleshoot the company Communications supervisor three.0. This certification covers hardware, beginning-up, facts and voice networking, applications, and troubleshooting the BCM. To current the certification, two checks necessity to live successfully completed: know-how requisites and Protocols for IP Telephony options, and Succession BCM three.0. The technology necessities and Protocols for IP Telephony solutions exam is an outline of convergence technologies.

NNCSS - CallPilot Rls. 2.0

This certification exams the means to Put in force, function, and troubleshoot the VoIP CallPilot 2.0. This certification covers hardware, administration, interoperability with Meridian 1 switches, and security of a unique website CallPilot system. To current the certification, two tests must live successfully achieved: Meridian Database and CallPilot 2.0.

NNCSS - Symposium cognomen middle Server or Symposium cognomen hub Server installation and protection

These two certifications eye at various the skill to implement, operate, and troubleshoot the Symposium cognomen hub Server. both certifications cover hardware, utility installing, administration, and protection of Symposium convene core Server 4.2, Symposium web client 4.0, and Symposium categorical three.0. besides the fact that children, the Symposium convene hub Server certification furthermore tests the architecture, customized configuration and integration of the server. To pass either of those certifications, one exam hold to live efficiently achieved: Symposium convene hub or Symposium convene core installation and maintenance, respectively.

NNCSS - Symposium convene hub TAPI/Agent or convene hub TAPI/Agent installing and preservation

These two certifications verify the aptitude to Put in force, operate, and troubleshoot the Symposium cognomen hub TAPI/Agent. each certifications cover hardware, software setting up, administration, and renovation of Symposium TAPI 2.three and Symposium Agent 2.three. however, the Symposium convene hub TAPI/Agent certification furthermore checks the structure, integration, and custom configuration of the TAPI/Agent. To traipse both of those certifications, one examination must live efficaciously completed: Symposium convene middle TAPI/Agent or Symposium convene core TAPI/Agent Inst/leading, respectively.

NNCSS - Symposium specific convene core or Symposium express cognomen middle installation and renovation

These certifications examine the aptitude to enforce, function, and troubleshoot the Symposium specific cognomen middle. both certifications cowl hardware, utility installing, administration, and protection of Symposium express convene hub four.2. despite the fact, the Symposium categorical convene hub certification furthermore checks the structure and integration of the cognomen middle. To current both of the certifications, one examination ought to live efficiently accomplished: Symposium categorical convene hub or Symposium categorical convene hub Inst and Maint respectively.

NNCSS - VoIP Multimedia communique Server (MCS) 5100 2.0

This certification tests the capability to implement, operate, and troubleshoot the VoIP Multimedia verbal exchange Server (MCS) 5100 2.0. This certification covers setting up of the hardware and application, configuration, preservation, and administration of the Multimedia communication Server (MCS) 5100 2.0. To traipse the certification, two assessments must live efficiently achieved: expertise standards and Protocols for IP Telephony solutions, and VoIP Multimedia verbal exchange Server (MCS) 5100 2.0. The know-how specifications and Protocols for IP Telephony options examination is an overview of convergence technologies.

NNCSS - VoIP Succession 1000/1000M Rls. 3.0 DB Administrator

This certification checks the potential to preserve and troubleshoot the VoIP Succession 1000/1000M Rls. three.0 DB Administrator. This certification covers the structure, configuration, upkeep, and administration of the Meridian 1, Succession one thousand Rls. 3.0, and Succession 1000M Rls. 3.0 the utilize of simple Alternate Route alternative (BARS) and network Alternate Route selection (NARS). To circulate the certification, two tests necessity to live successfully completed: expertise requisites and Protocols for IP Telephony solutions, and Succession a thousand/1000M Rls. 3.0 DB Administrator.

NNCSS - VoIP Succession one thousand/1000M Rls. three.0 setting up and upkeep

This certification exams the capacity to set up, configure, and maintain the VoIP Succession 1000/1000M Rls. 3.0. This certification covers the setting up, structure, configuration, preservation, and administration of the Meridian 1, Succession one thousand Rls. 3.0, and Succession 1000M Rls. three.0, cyber web Telephones i2xxx, and Optivity Telephony manager (OTM) 2.1. To circulate the certification, three tests must live efficaciously achieved: know-how specifications and Protocols for IP Telephony solutions, and Succession 1000/1000M Rls. 3.0 for Technicians, and Succession 1000/1000M Rls. three.0.

support professional

The aid expert certifications build on the specialist's expertise by demonstrating their aptitude to Put in force, operate, and troubleshoot an advanced Nortel Networks IP Telephony solution. The aid professional certifications reflect a candidate with six to twelve months of fingers-on journey with the means to lead or aid intermediate-level personnel to preserve complicated Nortel IP Telephony solutions.

NNCSE - CallPilot 2.0 Unified Messaging options

This certification assessments the aptitude to enforce, operate, troubleshoot and optimize the VoIP CallPilot Unified Messaging solution 2.0. This certification covers the installing, administration, interoperability, security, better techniques and feature usage for a multi web site CallPilot system. To pass the certification, the candidate necessity to first gain their NNCSS - CallPilot Rls. 2.0. consequently, the CallPilot 2.0 Unified Messaging solutions hold to live efficaciously completed to acquire this certification.

NNCSE - Contact middle

This certification checks the potential to Put into effect, operate, troubleshoot and optimize the Contact hub products. This certification covers the candidate's capabilities on the Symposium convene middle Server (SCCS)/Symposium express convene middle/Symposium net customer, Symposium TAPI service provider (TAPI SP), Symposium Agent, and the Symposium net hub Portal. To circulate the certification, the candidate ought to first acquire their NNCSS - Symposium cognomen hub Server and the NNCSS - Symposium convene hub TAPI/Agent certification. in consequence, the Contact middle examination hold to live correctly accomplished to reap this certification.

NNCSE - IP Convergence Succession 1000/1000M Rls. 3.0

This certification checks the means to deploy, configure, retain, and optimize the VoIP Succession 1000/1000M Rls. 3.0. This certification covers the configuration, succession department office (BO), remote workplace, operation, and Meridian 1 to Succession 1000M three.0 migration procedures for the Succession a thousand/1000M Rls. 3.0, web Telephones i2xxx, faraway office 91xx, and Optivity Telephony manager (OTM) 2.1. To pass the certification, the candidate hold to first obtain their NNCSS - VoIP Succession CSE 1000 Rls. 2.0 or the VoIP Succession 1000/1000M Rls. 3.0 installing & maintenance certification. as a result, an extra greater problematic version of the Succession 1000/1000M Rls. three.0 examination should live efficaciously achieved to achieve this certification.

within the IT trade, certifications are a routine to validate an individual's advantage within a exact area. The above Nortel IP Telephony certifications are probably the most tackle that may panoply the capabilities of an IP Telephony assist professional. These certifications couldn't substitute years of industry event, however they conclude deliver the foundation to support and manipulate Nortel Voice over IP solutions.

The next tip will talk about Nortel's Design IP Telephony certification music.

Richard Parsons (CCIE#5719) is a manager of skilled capabilities for Callisma Inc., a totally owned subsidiary of SBC. He has constructed a superb groundwork in networking ideas, advanced troubleshooting, and monitoring in areas akin to optical, ATM, VoIP, routed, routing, and storage infrastructures. rich resides in Atlanta GA, and is a graduate of Clemson institution. His legacy includes senior and predominant consulting positions at international network features, Lucent, and Callisma.


Bel Fuse (BELFB) this topple 2018 revenue conference convene Transcript | killexams.com real Questions and Pass4sure dumps

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picture source: The Motley fool.

Bel Fuse (NASDAQ:BELFB)this autumn 2018 earnings convention CallFeb. 21, 2019 11:00 a.m. ET

Contents:
  • organized Remarks
  • Questions and solutions
  • name participants
  • organized Remarks:

    Operator

    first rate day, and welcome to the Bel Fuse Inc. fourth quarter and full-year 2018 results conference name. modern day convention is being recorded. at present, i want to exhibit the convention over to Mr.

    Dan Bernstein, president and chief executive officer. gladden travel ahead, sir.

    Dan Bernstein -- President and Chief govt Officer

    thank you, Allison. becoming a member of me on the cognomen nowadays is Craig Brosious, their vice president of Finance; and Lynn Hutkin, their director of fiscal reporting. earlier than they start the call, i might like to hunt information from Lynn to traipse over the secure harbor remark. Lynn?

    Lynn Hutkin -- Director of fiscal Reporting

    thank you, Dan. decent morning, everybody. before they start, i might like to read here secure harbor statement. except for historic suggestions contained on this call, the concerns discussed on this cognomen corresponding to statements related to expected enlarge from the business's distribution channel, the results of the ERP system implementation and different high-quality industry and enlarge traits are forward-searching statements as described below the inner most Securities Litigation Reform Act of 1995 that involves dangers and uncertainties.

    exact effects could fluctuate materially from those projections. among the factors that might trigger genuine consequences to vary materially from such statements are: the market considerations facing their purchasers; the continuing viability of sectors that import on their products; the outcomes of company and economic conditions; difficulties associated with integrating currently obtained agencies; means and supply constraints or difficulties; product building, commercialization or technological difficulties; the regulatory trade ambiance; dangers associated with alien currency; uncertainties associated with prison proceedings; the market's acceptance of the business's original items and competitive responses to these original products; the influence of alterations to U.S. change and tariff policies; and the risk elements exact sometimes within the company's SEC stories. In smooth of the hazards and uncertainties, there may furthermore live no assurance that any forward-looking statement will, in fact, exhibit to live proper.

    We undertake no responsibility to update or revise any ahead-looking statements. They may additionally furthermore talk about non-GAAP effects throughout this convene and reconciliations of their GAAP consequences to non-GAAP effects were protected in their liberate. And simply earlier than turning the cognomen back to Dan, I simply desired to supply each person a heads up that their EBITDA reconciliation table in their accustomed release became fallacious. there were errors in that desk and a brand original release is popping out.

    So gladden sack that prefatory desk. So it truly is the third table, which is on web page 7 of the liberate.

    Dan Bernstein -- President and Chief govt Officer

    thanks, Lynn. earlier than going throughout the financials, i want to provide a short update on how the companies did from an operational standpoint this quarter and what they perceive going ahead. usual, we're very completely satisfied that they closed the 12 months with a different tenacious quarter, bringing their 2018 sales to $548 million, their larger revenue year for the understanding that 2015. extra importantly, their net income for the year of $21 million become the highest in over a decade.

    revenue bar nonexistent the route through the fourth quarter were $142.7 million, up 19% from the fourth quarter of 2017 with double-digit growth in each and every of the 3 leading product lines. Their backlog of orders remained mighty at $171.2 million at December 31, 2018, a surge of 17% from a 12 months in the past. The enhance in backlog is furthermore considered across every of their main product companies, which is a biddable barometer for different future increase. and searching via at the complete 12 months.

    Our Magnetic solutions neighborhood closed the 12 months with $24.4 million enhance in sales over 2017 stages led by elevated require for their built-in connector modules that are used in next-technology switching functions. revenue of their signal Transformer items hold been additionally potent birthright through 2018 as original courses with clinical and industrial purposes moved into complete production. they now hold furthermore increased the presence of their magnetic items via their distribution channels, which add to the 12 months-over-12 months sales growth. The backlog of orders from magnetic items grew by route of $9.7 million or 28% enhance for the understanding that the 2017 yr-end.

    Our Connectivity solutions neighborhood had yr-over-year revenue enlarge of $sixteen.four million. Their Cinch enterprise expanded profits via $8.2 million compared to 2017 led via mighty require for optical and copper products utilized in encryption, communication and threat detection radar applications. Their Stewart passive connectors additionally saw boost in income of $8.2 million from 2017 as better financial conditions in the edifice industry led to elevated require for their premise wiring customs throughout the year. The Cinch and Stewart enterprise furthermore capitalize from wonderful enlarge in earnings through their distribution channel in 2018.

    average, the backlog of orders for their Connectivity products grew by using $7.8 million, or 16%, in view that 2017 12 months-conclusion stages. Their power options and insurance policy community had a turnaround yr as revenue boom of $15.8 million from 2017 led this community to its first 12 months of sales enlarge when you consider that 2015. with the exception of the consequences of their NPS divestiture, sales for this group were up $21 million or 14% from closing 12 months, pushed by route of continued require for their power supplies in diversity of information core functions. sales of their DC to DC and circuit insurance policy products furthermore grew in 2018, offset by using a decline favorite for their custom modules.

    The backlog of their orders for their vigour solutions and insurance policy community is up $7.1 million or eleven% from 2017 yr-conclusion levels. From a profitability standpoint, overseas trade biddable points and a biddable adjustment draw the transition tax out to mitigate the larger labor and fabric charges that impacted their bottom line this yr. They proceed to hang pricing company as they drudgery through their higher cost stock on end. concerning the tariffs that had been implemented in 2018, they evaluate that about 10% of their consolidated annual revenues are at the second impacted.

    At this element, the bulk of these charges hold been handed along to their customers in the contour of invoice can charge. They proceed to monitor the situation carefully as they routine the tentative March 1 time restrict for the U.S. accomplishing a pretty biddable cope with China in bar nonexistent event extra increases on existing tariffs. typical, they wait cautiously confident with the continued income boom and profitabilities as they enter 2019.

    And with that, i would flip it over to Craig to rush in the course of the fiscal replace.

    Craig Brosious -- vice president of Finance

    Thanks, Dan. To supply a quick recap on income. revenue during the fourth quarter were $142.7 million. through geographic segment, North america earnings hold been $70.3 million, Asia income were $49.1 million and Europe hold been $23.3 million.

    with the aid of product neighborhood, Connectivity solutions income had been $46.four million, Magnetic solutions income were $forty eight.6 million and vigour options and insurance aim revenue were $47.7 million. indelicate profit margin expanded to 21.3% in the fourth quarter of 2018 as in comparison with 18.5% within the fourth quarter of 2017 as incremental earnings in 2018 ended in more suitable fastened can freight absorption offsetting larger labor expenses bar nonexistent over the yr. moreover, their indelicate earnings margin bar nonexistent through the fourth quarter of 2017 hold been impacted through inventory-related costs totaling $2 million in connection with keeping their stock on the lower can freight or net realizable cost. Their selling, commonplace and administrative expenses were $22.2 million or 15.6% of income as in comparison with $21.1 million or 17.6% of income in the fourth quarter of 2017.

    while the enlarge in SG&A costs bar nonexistent the route through the 2018 length $900,000 pertains to a decline in market price of their COLI policies, which changed into in accordance with the prevalent inventory market recreation during the fourth quarter of 2018. they now hold already began to peer this transpose in 2019. different offsetting components that affected that the variance in the fourth-quarter durations had been better legal and expert charges of $800,000 offset by using a lessen in unhealthy debt price of $500,000 and a discount in depreciation and amortization of $four hundred,000. On a go-ahead groundwork, they might forecast SG&A to rush between $20 million and $21 million per quarter within the nigh time period, barring any huge fluctuations in alien currency echange.

    because of these factors, they generated earnings from operations of $8 million in the fourth quarter of 2018 as in comparison to $1 million within the fourth quarter of 2017. pastime expense changed into -- i'm sorry, $1.4 million in the fourth quarter of 2018, down $900,000 from the identical duration closing yr. in case you withhold in mind, they refinanced their credit agreement in the fourth quarter of 2017, which ended in an acceleration of deferred financing cost amortization of $1 million during the remaining year's fourth quarter. Their provision for profits taxes became $2.four million for the fourth quarter of 2018 compared to $19.2 million bar nonexistent through final year's fourth quarter.

    the supply for revenue taxes birthright through the fourth quarter of 2018 was unfavorably impacted via taxes on international salary, the GILTI tax, partially offset by a abate within the U.S. tax price from 35% to 21% in 2018. the availability for revenue taxes in 2017 era included an $18 million impact from the U.S. Tax Cuts and Jobs Act, which become enacted on December 22, 2017.

    profits per participate for category a common shares was $0.31 per participate in the fourth quarter of 2018 as compared with a loss of $1.sixty six per participate in the fourth quarter of 2017. earnings per participate for class B common shares was $0.33 per participate within the fourth quarter of 2018 as compared with the want of $1.seventy four per participate in the fourth quarter of 2017. On a non-GAAP groundwork, which excludes inevitable peculiar and different nonrecurring items, EPS for category A shares become $0.37 per participate in the fourth quarter of 2018 as compared with the loss of $0.09 per participate in the fourth quarter of 2017. On a non-GAAP groundwork, EPS for class B shares turned into $0.39 per participate in the fourth quarter of 2018 as in comparison with a want of $0.10 per participate within the fourth quarter of 2017.

    And now i would like to travel through some stability sheet and cash circulation gadgets. Their money and cash equivalents balance at December 31, 2018, changed into $fifty three.9 million, a lessen of $15.4 million from December 31, 2017. birthright through 2018, they made payments of $9 million towards their fantastic debt steadiness. They furthermore used cash for capital charges of $11.6 million, dividend funds of $3.3 million and hobby funds of $four.8 million.

    money owed receivable were $ninety one.9 million at December 31, 2018 as compared with $78.8 million at December 31, 2017. Days income striking hold been 59 days at December 31, 2018, compared to 60 days at December 31, 2017. The boost in debts receivable stability changed into generally because of the bigger revenue volume within the fourth quarter of 2018 as compared to the fourth quarter of 2017. Inventories were $120.1 million at December 31, 2018, up $12.three million from December 31, 2017.

    In January of 2018, they adopted the original income cognizance regular, which hastens the timing during which they earnings become identified and the corresponding liberate of comprehensive items from their stock balance concerning items held at customer control hubs. except for the results of this adoption, their stock stability would hold elevated by $23.4 million from December 31, 2017, essentially uncooked materials and work-in-growth in keeping with the enhance well-known for their products in 2018. accounts payable had been $fifty six.2 million at December 31, 2018, up $8.2 million from its degree at December 31, 2017 because of the raise in raw material purchases. Bel's total fantastic debt turned into reduced with the aid of $744,000 during the fourth quarter, bringing the balance down to $116 million as of December 31, 2018, aside from deferred financing cost.

    ebook cost per share, which is calculated as stockholders' equity divided by route of their combined A and B classes of prevalent inventory impressive, become $14.39 per participate at December 31, 2018 as in comparison to $13.13 per participate at December 31, 2017. And now i want to exhibit the cognomen returned to Dan and open the convene for questions.

    Dan Bernstein -- President and Chief government Officer

    yes. conclude they open up the require questions, please, Allison? 

    Questions and answers:

    Operator

    actually, sir. [Operator instructions] they are able to now seize their first question from Sean Hannan from Needham & enterprise. gladden travel ahead, sir.

    Sean Hannan -- Needham and enterprise -- Analyst

    yes. Thanks. respectable morning, everyone. Dan, i used to live looking to perceive if I might hunt information from you might provide us with a tiny bit of detail across the phase.

    i conclude know you offered some on your prepared feedback. can you in bar nonexistent probability amass into a bit bit extra specificity when it comes to how had been you feeling with each of these section nowadays and the actions they ramp birthright here within the first quarter and in '19. and perhaps how that may additionally hold trade or could live different versus what you were expecting probably just a brace of months in the past? Any perception there could live very effective. Thanks.

    Dan Bernstein -- President and Chief govt Officer

    adequate. Of path, bar nonexistent of their product businesses and bar nonexistent of the subdivisions inside the product corporations, a majority, i would say, 80% of bar nonexistent were very robust. they now hold one community, is the Modular group and the DC to DC neighborhood out of Italy which hold some tremendous clients that they misplaced, but that hasn't been the comfort to conclude with the market conditions simply on account of the situation with these clients. So ordinary everything has been, as you live vigilant of, extraordinarily fine.

    Going into this quarter and subsequent quarter, January become a very -- they saw a tenacious January, and once again, they suppose they conclude not perceive any alterations within the first quarter. The handiest concerns that they conclude hold is there are some IC businesses that are seeing some softening in the market and they conclude hear some rumblings that there may live too a lot inventory in the pipeline. but to this point it has not affected their revenue or backlog. So again, it's why I consider we're a bit wonderful for the first quarter and for instance, I suppose nigh out after that.

    Sean Hannan -- Needham and company -- Analyst

    adequate. impartial ample. Now as they seem into the power neighborhood, it is definitely always a topic on each and every name. there's a all lot that you've done when it comes to correcting the nice concerns from one of the vital acquisitions you've got taken on, there's a worthy deal you could hold been doing to step-up executions, plenty that you hold executed in incrementally successful original designs and into original programs some of which has been getting some momentum.

    and that i suppose you said that a bit bit earlier today. What extra may silent they await within the trajectory of these organizations? Is there the comfort within the history that's incrementally being labored down or is obtainable a bogey that might accelerate up the boom trajectory that you're now atmosphere into today? Or how should silent they consider about how this continue to enhance as a product section for you? Thanks.

    Dan Bernstein -- President and Chief govt Officer

    good enough. So the verve community, again, as they brought up over the ultimate two or three years, they reliance very strongly that has the best boom expertise for Bel from a accurate-line standpoint. On the power, they did hold is after they acquired the company previous administration truly failed to hub of attention on pleasant and customer service. And it took us a very long time to exchange that; a, first change their manufacturing unit then exchange the client opinion, and over the final 18 months, they now hold bar nonexistent their purchasers are back and believe Bel to live a power corporation.

    I feel two issues that they now hold achieved that they now hold changed these days. One became, I consider, as they hold been so desperate for earnings, they took a shotgun approach and really Put bar nonexistent check on their R&D community without getting the ilk of effects that they would like. So what we've performed is, truly long past from much greater chosen routine of what consumers you necessity to deal with, how they fit into us and should they live long-time era shoppers? With that said, they are streamlining their R&D community because they will not hold to travel with the southbound method, they comprehend what precisely engineers they deserve to steer these products as they circulate ahead. the key hardship now could live that they conclude hold two or key key customers that may travel anywhere from $eight million to $12 million, $13 million.

    And once we're talking about statistics middle-category of customer, they conclude hold immense customer classification of valued clientele. again, those fluctuate very immense from a earnings standpoint. once more, however, they conclude contemplate that we've located ourselves much more within the market, and currently I feel they now hold 90 NDA signed on high-effectivity vehicles and we're starting to perceive that enterprise travel from $three million to $5 million. So we're hoping that would double once more, offers us a lot more diversification, and they are working with different information hub classification of customers.

    So they amass that greater assorted. So again, they are silent taking pictures. Their goal has bar nonexistent the time been to amass vigour to that consistent 10% enlarge over a two to three-12 months period.

    Sean Hannan -- Needham and enterprise -- Analyst

    good enough. that's beneficial. and then closing query birthright here. just to perceive if i will live able to amass some standpoint round a customer of yours without delay or ultimately.

    Huawei, I recall you might live now not necessarily even a 5% consumer, but are you able to focus on how conclude they play into your enterprise traditionally? And is there the comfort that they should silent consider of thinking about that relationship or income technology and maybe by some means tied to them on a go-forward groundwork? Thanks.

    Dan Bernstein -- President and Chief executive Officer

    neatly, I suppose, again, being a chinese language business, I contemplate they are inclined to travel along with chinese providers in China. i know, for instance, they offered their verve provide neighborhood to Emerson about six years ago, and now former Huawei individuals hold their own verve give company. So they know it's a troublesome nut to crack. They conclude some ICM enterprise, however no longer vast in any respect.

    And for us, it's going to live a tenacious advantage as a result of they contemplate people like Nortel, Cisco should silent prefer up the company that they're losing. So i conclude know there are inevitable nations, Czech Republic, even Canada and the U.S. how they view Huawei going ahead. And that they cannot buy tackle from Huawei for 5G, they will doubtless travel with -- I failed to add up to Nortel, I hunt information from for forgiveness, Nokia, that Nokia and Cisco will likely select up that slack and might live Alcatel, and these multinational non-chinese language purchasers they conclude immense quantity of industry with them.

    So we're hoping that their industry should silent enlarge as more and more 5G is delivered.

    Sean Hannan -- Needham and company -- Analyst

    Very first rate. Thanks so tons, folks.

    Operator

    [Operator instructions] And they will now seize a question from Hendi Susanto from G. analysis. gladden travel forward.

    Hendi Susanto -- G. analysis -- Analyst

    first rate morning. Dan, you commute to China a worthy deal. How conclude you signify your China market now? How different is it in comparison to a typical 12 months?

    Dan Bernstein -- President and Chief executive Officer

    We at bar nonexistent times -- for us -- bar nonexistent over the realm, I imply, Europe and China there may live so a lot uncertainty and how they reliance in Donald Trump and the job he's doing. there's giant amount of anxiousness. For us again, for the China market, or not it's always been very complicated to raze into that market as a result of the pricing parameters that you've got promoting to, again, a chinese language consumer. although, a biddable component can live 35% of their sales travel to China, but it surely goes throughout the CEM like the Flextronics or Hon Hai, Foxconn, and those are non-chinese groups.

    youngsters, they conclude -- they are starting to perceive more americans eye at China in a discrete easy. They recognize the ODMs in Taiwan, they hold majority of their production in China. They at the second are pitiable a few of that creation lower back into Taiwan. They perceive other multinationals relocating products round to amass across the tariffs.

    So when you've got production in Malaysia, utilize that for bar nonexistent items coming to the States after which you utilize your China production to travel into Europe and the a long route East market. but once again, no one likes uncertainty and that without query with the tariffs there's giant amount of uncertainties and that's not first rate for anyone.

    Hendi Susanto -- G. research -- Analyst

    got it. after which Dan, given solid income growth and your backlog boom in 2018 and existing ERP implementation, how a biddable deal development in indelicate margin and working margin they should await in 2019?

    Dan Bernstein -- President and Chief executive Officer

    i will depart that to my accounting neighborhood here.

    Craig Brosious -- vice president of Finance

    yes. I consider assuming the within your budget sales enlarge that we're expecting, moderate income increase, I believe they hold some leverage means to movement the indelicate margin up to maybe a point, aspect and a half. once more, lots of their construction costs are primarily based in the -- in China and counting on which approach the trade agreements go, it may hold an outcome on the change fees that they should deal with on the can freight of that -- on the labor costs, exceptionally. So barring any massive moves in these change charges, we've opportunities to extend margins a bit bit.

    Hendi Susanto -- G. research -- Analyst

    after which a further question on charge. So I contemplate Bel Fuse is coping with enhance in labor charge, and that i suppose that has been there for a long time after which you were mitigating or taking movements or improved your labor charge. after they traipse through like 2019, when can they examine on an apple-to-apple 12 months-over-12 months assessment in regards to the labor can charge? And like how -- and then live certain you live in a position to quantify how an snide lot labor freight become?

    Craig Brosious -- vice chairman of Finance

    I believe they -- to amass to an apples-to-apples comparison, they are able to likely should amass within the third quarter of this year because they had freight raises going into impact within the first and second quarters of 2018. So I feel as soon as they amass to the third quarter, they amass some low cost comparatives.

    Lynn Hutkin -- Director of fiscal Reporting

    The most efficient aspect to add there's, in 2019, we're furthermore experiencing elevated labor freight in Mexico so that you can finger the 2019 length, however changed into not there birthright through the 2018 period. So they hold that as smartly.

    Hendi Susanto -- G. analysis -- Analyst

    adequate. and then the majority of the tariff cost has been passed to clients. can you quantify how a worthy deal has been handed and what's next?

    Dan Bernstein -- President and Chief executive Officer

    I consider it's been about $7.eight million, in that latitude.

    Lynn Hutkin -- Director of fiscal Reporting

    In 2018, it become about $2.four million, in total for 2018, in order that become a partial -- that was a partial 12 months.

    Craig Brosious -- vice chairman of Finance

    So like Dan had mentioned previously, most of their sales as a minimum coming out of China don't become without delay into the U.S. So we're not enormously impacted through the tariffs. So they hold been capable of -- basically $2.5 million or in order that they needed to add.

    Hendi Susanto -- G. analysis -- Analyst

    good enough. acquired it. thanks.

    Operator

    [Operator instructions] It appears there aren't any additional questions. Mr. Bernstein, i would like to exhibit the convene back to you for any additional or closing remarks.

    Dan Bernstein -- President and Chief govt Officer

    thank you for joining us nowadays, and they seem to talking to you sooner or later. thanks to your time.

    Operator

    [Operator signoff]

    length: 29 minutes

    call members:

    Dan Bernstein -- President and Chief government Officer

    Lynn Hutkin -- Director of monetary Reporting

    Craig Brosious -- vp of Finance

    Sean Hannan -- Needham and enterprise -- Analyst

    Hendi Susanto -- G. research -- Analyst

    greater BELFB analysis

    this article is a transcript of this convention convene produced for The Motley fool. while they try for their fatuous premier, there could live mistakes, omissions, or inaccuracies during this transcript. as with bar nonexistent their articles, The Motley fool does not assume any responsibility for your utilize of this content material, and they strongly embolden you to conclude your personal analysis, together with listening to the convene yourself and analyzing the business's SEC filings. gladden perceive their phrases and conditions for additional details, together with their mandatory Capitalized Disclaimers of liability.

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    Strongbridge Biopharma plc (SBBP) Q4 2018 Earnings Conference convene Transcript | killexams.com real questions and Pass4sure dumps

    Logo of jester cap with thought bubble.

    Image source: The Motley Fool.

    Strongbridge Biopharma plc  (NASDAQ:SBBP)Q4 2018 Earnings Conference CallFeb. 26, 2019, 8:30 a.m. ET

    Contents:
  • Prepared Remarks
  • Questions and Answers
  • Call Participants
  • Prepared Remarks:

    Operator

    Good morning, ladies and gentlemen, and welcome to the Strongbridge Biopharma Corporate Update and Fourth Quarter 2018 Earnings Conference Call. At this time, bar nonexistent participants are in a listen-only mode. Later they will conduct a question-and-answer session and instructions will result at that time. (Operator Instructions) As a reminder, this convene will live recorded.

    I would now like to interject your host for today's conference, Ms. Lindsay Rocco of Elixir Health Public Relations. You now may begin.

    Lindsay Rocco -- Investor Relations

    Thank you and biddable morning, everyone. They are pleased that you could combine us today for Strongbridge Biopharma's fourth quarter and complete year 2018 earnings conference call. Joining me from Strongbridge this morning are Matthew Pauls, President and Chief Executive Officer; Dr. Fred Cohen, Chief Medical Officer; and Brian Davis, Chief financial Officer.

    Before they begin, I would like to remind you that during this call, the Company will live making forward-looking statements that are topic to risks and uncertainties that may understanding actual results to disagree from the results discussed in the forward-looking statements. Reference to these risks and uncertainties are made in today's press release and disclosed in detail in the Company's fitful and current event filings with the U.S. Securities and Exchange Commission.

    In addition, this presentation includes non-GAAP financial measures. This presentation is not intended to live a substitute for financial results presented in conformity with generally accepted accounting principles in the U.S. Investors and potential investors are encouraged to review the reconciliation of the pro forma financial measures included in the Company's earnings release. The most directly comparable GAAP information and a reconciliation between the non-GAAP and GAAP figures are included in the Company's fourth quarter 2018 earnings release, which has been furnished on contour 8-K.

    I will now revolve the convene over to Matthew Pauls.

    Matthew Pauls -- President and Chief Executive Officer

    Thank you, Lindsay. biddable morning everyone and thanks for joining us. For today's call, I'll commence by providing a brief summary of their fourth quarter and complete year 2018 highlights and results. And then we'll revolve the convene over to Dr. Fred Cohen, their Chief Medical Officer, to discuss the ongoing aspect III clinical development program for RECORLEV. Brian Davis, their Chief financial Officer, will then provide a financial overview. They will then open up the convene for questions.

    With that, let me start by proverb that Strongbridge had a tenacious fourth quarter from a clinical, commercial and financial perspective, which is a reflection of their momentum and overall success throughout the past year. As you will hear from the team today, their accomplishments in 2018 demonstrate the value of their rare disease strategy and hold positioned us for future growth as they continue to identify, develop and commercialize vital treatments for rare diseases. Leveraging the momentum from final year, they entered 2019 with a focus on progressing the development of RECORLEV for the treatment of endogenous Cushing's syndrome.

    And getting into their most notable fourth quarter accomplishments, let's start with the Novo Nordisk transactions. In December, they significantly strengthened their balance sheet with the sale of the U.S. and Canadian rights of MACRILEN to Novo Nordisk. As previously mentioned, a portion of the upfront cash payment of $145 million from Novo Nordisk to Strongbridge was used to repay bar nonexistent outstanding debt. Other key terms from the transaction include that Strongbridge will receive royalties on MACRILEN sales through 2027. And in addition, Novo Nordisk purchased 5.2 million ordinary shares of Strongbridge at a purchase price of $7 per share, resulting in indelicate proceeds of $36.7 million.

    Another vital key strategic term of the transaction is that Novo Nordisk will fund Strongbridge's 23-person rare endocrine commercial realm organization over the next three years to promote MACRILEN in the United States. This aligns with the Company's objective to maximize the potential of MACRILEN, while preparing for the potential regulatory approval of RECORLEV in endogenous Cushing's syndrome, a rare condition that's often treated by the same endocrinologist that diagnose and treat adult growth hormone deficiency.

    Onto their rare neuromuscular franchise. KEVEYIS, their first commercial product, enabled us to build out a rare neuromuscular franchise, which continues to live a strategic pillar for the Company. They are committed to serving the needs of the primary fitful paralysis, or PPP community, which is comprised of an estimated 4,000 to 5,000 currently diagnosed patients in the United States. As they prepare for the regulatory filing of potential launch of RECORLEV, there are many parallels and learnings that they hold garnered from the KEVEYIS chance that they hold and will continue to leverage across their business.

    Additionally, they believe that the suffer and lore gained from launching KEVEYIS best positioned Strongbridge to acquire the rights to MACRILEN early final year, before selling the rights to Novo Nordisk at the cease of the year. As piece of their life cycle management planning for KEVEYIS, they are executing on a number of initiatives with the primary objective of maximizing the value of KEVEYIS over time. They believe that by the cease of 2019 or into early 2020 that they will live in a position to provide an update on their life cycle management progress.

    Our investment approach with KEVEYIS focuses on three key areas. Specifically, they are focusing their KEVEYIS commercial investment on, one, utilizing sophisticated data to identify physicians that treat PPP; two, fully leveraging their CareConnection patient services model; and three, engaging the PPP community through both patient advocacy, as well as targeted social media. They eye forward to executing against their 2019 plans and believe that KEVEYIS will generate a positive contribution margin by the cease of the first quarter of 2020.

    So with that I'll revolve the convene over to Dr. Fred Cohen, their Chief Medical Officer, to discuss their clinical development progress for RECORLEV, which they believe continues to hold the potential to live a first-line, first-choice therapy for patients with endogenous Cushing's syndrome.

    I will now revolve the convene over to Fred.

    Fredric Cohen -- Chief Medical Officer

    Thank you, Matt. biddable morning, everyone. As previously announced in the third quarter, the pivotal aspect III SONICS study of RECORLEV for the treatment of endogenous Cushing's syndrome met its primary endpoint, with urinary free cortisol or UFC confirmed (ph) as prevalent among 30% of the intent to treat population at the cease of the six-month maintenance phase.

    Detailed initial results from the SONICS study were presented in October at the European NeuroEndocrine Association Annual Meeting, with additional data presented at the European Network for the study of Adrenal Tumors Annual Meeting in November. These analyses illustrated the propitious effects of RECORLEV on hypercortisolism and its comorbidities, particularly sustained improvements in markers of cardiovascular risk, such as LDL-cholesterol, hemoglobin A1C and cadaver weight.

    Further SONICS results from the cease of maintenance analyses are planned for presentation at the International Pituitary Congress and the Endocrine Society's Annual Meetings in late March, and at the American Association of Clinical Endocrinology Meeting in April. These results will highlight additional benefits of RECORLEV on the signs and symptoms of hypercortisolism.

    Additionally, submission of a manuscript of the primary efficacy and safety data from SONICS to a peer-reviewed journal is anticipated in the first half of 2019. One-year data from the completed SONICS study are expected to live available in the first half of 2019. These data will include findings from the six-month extended evaluation phase, which is primarily intended to characterize the long-term safety, tolerability and benefit-risk profile of RECORLEV.

    From a regulatory standpoint, a ilk C meeting with the FDA is planned within this quarter to hunt guidance on the path forward to obtain marketing approval for RECORLEV in the United States, and that process is on track. They anticipate providing an update in the second quarter.

    Finally, the receipt of top line results from the aspect III LOGICS study remains on track for the fourth quarter of 2019. As a reminder, LOGICS is a double blind affliction with no planned interim analyses prior to the receipt of these anticipated results.

    And with that, I will now revolve the convene over to Brian Davis for a financial overview.

    A. Brian Davis -- Chief financial Officer

    Thank you, Fred. Their press release accommodate details of their financial results for the fourth quarter and complete year 2018. Rather than read bar nonexistent of those details, my comments will hub on a few highlights.

    As notable in the press release, their guidance for KEVEYIS revenues in 2019 is in the $18 million to $20 million range. They hold significantly improved their financial and strategic flexibility as a result of the cash proceeds and anticipated future payments from their transactions with Novo Nordisk, as well as the repayment in complete of their outstanding debt. They ended 2018 with $122.5 million of cash, cash equivalents and no outstanding debt. As for cash runway, they believe the combination of their existing cash resources, anticipated KEVEYIS revenues and payments from Novo Nordisk, as well as the continued prudent management of their operating expenses will provide enough capital to support their operations, at least through the first quarter of 2021.

    And Catherine, with that, they are now ready to open up the convene for questions.

    Questions and Answers:

    Operator

    (Operator Instructions) And their first question comes from Esther Hong with Janney. Your line is open.

    Esther Hong -- Janney -- Analyst

    Hi, biddable morning. Thanks for taking my questions. So with respect to the ilk C FDA meeting over RECORLEV, can you provide additional details on your expectations, and then, any potential logistics regarding accelerator approval? And then the second question is, any updates on industry development plans in 2019? Thanks.

    Matthew Pauls -- President and Chief Executive Officer

    So Esther, this is Matt. Thank you for the questions. Let me seize them in transpose order. With respect to industry development, they obviously don't comment on any industry development-related projects that they may live working on. I conclude contemplate that their history here at Strongbridge -- as they continue to build the Company is that they are energetic in looking at opportunities and that continues. And that's bar nonexistent I'll allege on that front. I will hold Dr. Cohen comment on the ilk C regulatory process and timing.

    Fredric Cohen -- Chief Medical Officer

    Sure. So as I've just -- they conclude aim to hold the discussion with the FDA in the first quarter of this year, and then following digestion of that and then any clarifying dialog they necessity to hold with the FDA, they aim to update investors by the second quarter with the path forward, as they said. In terms of their base case, just to reiterate, they are anticipating that the FDA will steer us toward the necessity for both the complete SONICS as well as the complete LOGICS study for being in hand and included within NDA. Again, that's the base case. The upside case for us that they believe is supported with the unmet medical need, the route that SONICS was designed in terms of using a surrogate endpoint that's been established, and the precedent within this division of allowing approval on the basis of the unique open label study, they believe that there is an upside case where there could live an accelerated pathway toward the filing, where they base it primarily just on the SONICS, to your point around accelerator approval. Again, they conclude contemplate that the dialog that we're anticipating with the FDA in this quarter will beget that pathway lucid for us and then we'll update you guys accordingly.

    And with respect to timing, that's just so -- in the expedited or accelerated upside case, clearly they would live working arduous to amass it -- amass the NDA filed as quickly as possible, probably realistically why they would like to hold it filed by the cease of the year, at the cease of 2019, it probably would live more like an early 2020-ish. More details to reach on that, obviously, as they hold more clarity. In the base case, it would live about a year later than that. I hope that helps.

    Esther Hong -- Janney -- Analyst

    It does. Great, thank you.

    Fredric Cohen -- Chief Medical Officer

    You are welcome.

    Operator

    Thank you. And their next question comes from Annabel Samimy with Stifel. Your line is open.

    Nick Rubino -- Stifel -- Analyst

    Good morning, everyone. This is Nick Rubino on for Annabel Samimy. Thanks for taking their question. First, how the efforts to educate physicians on titration helped patient retention. Are you silent seeing attrition due to the side effects and how conclude you perceive those dynamics playing out 2019 and beyond? And then second with the one-year SONICS, you had mentioned the safety pieces, but are they getting efficacy measures as well? And then, if I can just sneak in a quick rapid one, with the MACRILEN revenue numbers you reported this quarter, are those purely royalty revenues or did those include complete sales from October and November? Thanks.

    Matthew Pauls -- President and Chief Executive Officer

    Thanks for those questions, Nick. Let me give you a tiny insight on the first question regarding KEVEYIS. They learned a lot on the KEVEYIS fronts in 2018 regarding both KEVEYIS as well as primary fitful paralysis. And one of the key learnings which you well said was around the need, often to travel a tiny bit lower and a tiny bit slower in the titration period. And, I'll hunt information from Dr. Cohen just to comment briefly on that. I think, they hold some learnings from aspect III affliction and then from the clinical -- not just clinical instant -- in the clinical trial, but furthermore in the commercial utilize too. So, Fred, conclude you want to comment on that?

    Fredric Cohen -- Chief Medical Officer

    Yeah. Yeah, sure. Great. So one of the things that they learned was that there are a significant minority of patients who experienced adverse reactions from the drug early on in the therapy. And one of them -- one of those reactions that's common is on -- a confusion on mental fog, if you will, that occurs. It's a evanescent response to the drug until the brain can sort of equilibrate and become used to the drug. But when it occurs, it needs to live addressed, it needs to live managed, and the best route that they know how to manage it is by lowering the dose of the drug.

    Well, it took us a while, I think, number one, to recognize that this was a reaction that was amenable for some patients discontinuing from the drug. And once they did recognize that, they Put in status a chain of educational efforts aimed at physicians initially and then later direct-to-patient education and supervision through the utilize of, for example, patient ambassadors that hold given their time generously to aid educate other patients. And so we're making worthy progress. I think, it's impartial to allege we've seen already changes in the route the titrations are going. And we've gotten feedback from patients who are now able to overcome the initial side-effects and hold stayed on the drug, because they are seeing benefits from it in many cases. So, I hope that addresses that piece of that question.

    Nick Rubino -- Stifel -- Analyst

    Yes, that's great. Then, with regards to the --

    Matthew Pauls -- President and Chief Executive Officer

    Yes, the MACRILEN revenues during the fourth quarter were product sales by Strongbridge. There were no royalties in their revenues for the quarter.

    Fredric Cohen -- Chief Medical Officer

    Yes, there was furthermore a question you had about the 1-year RECORLEV data. So on the top line data that they will live sharing with you will include primarily safety data. But furthermore they did measure some efficacy data as well, including urine free cortisol, as well as those comorbidity markers. And I'm pretty certain we'll live sharing that with you at the time they release the top line results.

    Nick Rubino -- Stifel -- Analyst

    Alright. Great. Thank you guys.

    Matthew Pauls -- President and Chief Executive Officer

    Yes, thanks for the questions.

    Operator

    Thank you. And their next question comes from Hartaj Singh with Oppenheimer & Company. Your line is open.

    Hartaj Singh -- Oppenheimer & Company -- Analyst

    Great, thanks. Thanks for the question and a biddable year. Just a brace of questions, Matt I've got. On your interactions with the FDA prior to this meeting, I assume you might hold already submitted a sort of a briefing package and benign of there hold been some interactions back and forth. Can you just give some color on, sort of, the gist of those interactions and what are some of the questions that maybe you're asking or FDA is wanting to live addressed prior to the actual meeting? And then a second question, just on KEVEYIS, to result up with the previous question. Matt, can you just give some color on, sort of, original patients, continuing patients, what sort of -- how many patients are staying on drug, on average, just any color around what that dynamic is, because it seems that the drug is growing quarter-on-quarter. And then just your thoughts about that going forward. And then just a quick housekeeping question after that. Thank you.

    Matthew Pauls -- President and Chief Executive Officer

    Great, thank you Hartaj. So on the regulatory question related to RECORLEV. As a gauge course for us, they don't comment on the interactions prior to having their final interpretation of the dialog. So more to reach in the second quarter. And I think, Fred articulated well earlier what their base case assumptions are meeting both trials and the upside case around an accelerated potential approval, given the significant unmet necessity in Cushing syndrome, UFC being a stated accepted surrogate endpoint by the FDA, resoundingly positive, and they contemplate compelling SONICS data. And then, in this division, in the review of Cushing's syndrome, unique affliction approvals. So that's where we're at and we'll provide an update in the second quarter.

    And then with respect to KEVEYIS -- and your question on KEVEYIS. So what they know is that there -- they are confident there are 4,000 to 5,000 patients currently diagnosed with PPP. They are seeing original patients regularly reach onto KEVEYIS. And they are doing a much better job, as Fred mentioned, with respect to patient-to-patient interaction, patient-to-physician interaction, recommendations around maybe lower and slower titration or down titration. So they are seeing patients more often than not -- now wait on the drug through that benign of an interim period.

    And so, the immense focus for us here is being smart and choiceful about their investment even with respect to KEVEYIS, because it's vital for many reasons to try to drive KEVEYIS to profitability on a stand-alone basis as quickly as possible. And we're confident that we're on that path by the cease of the first quarter of 2020. And parallel to that, given the fact that there are no other drugs really that are in development for the treatment of this ultra-rare genetic neuromuscular condition, PPP, they are working very feverishly and hard, as we've said previously, around life cycle management opportunities. They would like to hold the chance to hold more runway with KEVEYIS. So more to reach by the -- probably by the cease of the year, again, maybe into 2020 on their life cycle management plans. But this is a market that prior to us relaunching the drug really had no investment ever, was disorganized, unstructured. And we're confident that we're on the path to structuring it, organizing it and getting KEVEYIS to profitability, so that we're being smart and choiceful and sage with respect to their investment.

    Hartaj Singh -- Oppenheimer & Company -- Analyst

    Great. And Matt, that's worthy color. Just a follow-up on that. So roughly speaking, are you sort of seeing patients that are coming that are original to KEVEYIS being equal to patients dropping off, or is there less of a drop-off, just what's the dynamic there between the original and the continuing patients and the patients that are leaving, whether it's titration or for other issues?

    Matthew Pauls -- President and Chief Executive Officer

    So, they -- the trend is that more patients are staying on the drug than off. And that's based on the interventions, really in -- I guess in the back half of the third quarter and the fourth quarter by us, and of course to-date. So what we're -- the patient identification and identifying patients who are very motivated and physicians that are motivated and then providing the very tenacious even of support and service for them through that process, given the potency of KEVEYIS. I add up to the drug really works. It really works. They are having success getting patients through that short -- I don't know -- for a four-to-six-week period-ish, that range. But it's upwards of eight weeks.

    Hartaj Singh -- Oppenheimer & Company -- Analyst

    Got it. And then just one housekeeping question on -- just how to contemplate about operating expenditures, sort of, going forward for the year, just any thoughts there? And again, thank you so very much.

    Matthew Pauls -- President and Chief Executive Officer

    Yes, Hartaj. This is Brian, Hartaj. Thanks for that. So, on the cash basis, as I mentioned, we're looking at a runway that takes us through the first quarter of 2021. I contemplate they hold the capitalize of the Novo Nordisk subsidy coming online here in 2019 to offset the commercial pains around MACRILEN. And so we'll hold a tiny transition working through Q1 to amass down on a cash char basis. But they feel pretty comfortable in that low-to-mid teens area as they traipse forward. In fact, if you seize that $122 million cash balance and just by simple averaging over the subsequent nine quarters through the first quarter of 2021 that comes up to about $13.5 million. So a tiny more in this year, reflecting the transition down, reflecting we've got some increased RECORLEV program expenses (inaudible) elevated water mark, if you will, for the RECORLEV program, because they hold SONICS and LOGICS and OPTICS running simultaneously, but obviously SONICS expense is winding down now that the one-year data will live coming through. So again, enough cash to amass us at least through the first quarter. And obviously, we'll hold more definition on that as they travel along as to how much more at least it can be.

    Hartaj Singh -- Oppenheimer & Company -- Analyst

    Great. And I really esteem it. Thank you very much.

    Operator

    Thank you. And their next question comes from Liisa Bayko with JMP Securities. Your line is open.

    Liisa Bayko -- JMP Securities -- Analyst

    Hi, congratulations on the quarter. Just a brace of questions for me, mainly about KEVEYIS. So first of all, I want to allege congratulations, I add up to you've made this into a product that reached $20 million this year, which is certainly a lot higher than where you thought the product brace of years ago. They technically were only talking about $1 million. So it's obvious that you've done a tremendous job in creating this market. But again (ph) your guidance a tiny bit, for this year, looks like $4.4 million is the benign of what you're coming off 4Q (ph). Your guidance of $18 million to $20 million implies a tiny bit of slowing growth. So is that -- are patients adds silent happening at the same rate or is that lower, are you having -- struggling to find more patients or is it based on -- basically from your comments, I'm thinking maybe less revenue per patient because of dose titration. What's the benign of dynamic with add indications or revenue per patient? How does that -- what's sort of underlying the guidance?

    A. Brian Davis -- Chief financial Officer

    Yes, this is Brian. So again, we're continuing the biddable news, is find patients. And they feel really biddable about the realm coerce they hold in status and they're performing very strongly, as Matt indicated in his comments and in the prior answer. We've had a lot of learning in this market and working through how best not only to attract patients, but furthermore to retain patients. So they were conscious of the revenue compass that they Put out there, $18 million to $20 million and where we've reach off of this year, we're going to live conservative in their approach, But the patient retention piece takes time and they contemplate we're working through it.

    On the expense side, they hold focused their investment and made decisions to abate the territories to aid beget certain they amass to a positive contribution margin or a profitability standpoint for the product. They went from 21 down to 17 territories. They focused their marketing expenses to those -- really targeted toward the patient, in order to aid bar nonexistent of the revenue expenses to line up. So, we'll withhold working through it, but they feel biddable about their aptitude to not only hit this range, but furthermore to amass this product to live one that's a profitable one. And as you pointed out at the beginning, it was a very challenging market to enter into. You're quite correct. Before they had acquired the drugs -- the drug, I should say, its sales had been less than $1 million in a year. So, yes.

    Matthew Pauls -- President and Chief Executive Officer

    Yes, so Liisa, the other piece on that to note is, as I mentioned, in parallel, they are looking at life cycle management opportunities and we'll update the market probably by the cease of the year or in early 2020. And if there are potential opportunities to extend the life and runway of KEVEYIS, they will obviously, probably revisit their investment strategy with respect to the brand. But birthright now, it is to amass it to profitability as quickly as practicable and to grow the top line, which they will conclude both. And exiting the year, the low cease of the range, we're tracking already to the low cease of the range. So hopefully, there will live some -- even more enhanced or increased momentum as they travel the year.

    Liisa Bayko -- JMP Securities -- Analyst

    Okay, impartial enough. And then, I guess, as you eye longer-term, are you silent thinking this product is benign of easily a brace hundred million or conclude you hold some other benign of target in mind longer-term now that you've had more suffer selling the drug? Just thinking about how, benign of, directionally where they should live headed in terms of modeling. Thanks.

    A. Brian Davis -- Chief financial Officer

    I contemplate -- this is Brian. I think, there's a brace of things there, Liisa, that really play into that. So one is the patient penetration. So they contemplate we've got an chance and we're really just at the beginning stages of it in terms of patient penetration. Now Matt and Fred were taking a tiny bit earlier about life cycle management opportunities, having a longer commercial runway will certainly allow us the chance to reach peak sales levels over a longer era of time that they hold (inaudible). We're just operating with the current regulatory exclusivity. I think, the other piece that obviously plays into in this environment is around the price of the drug. And I would note, they continue to live very cautious in their thinking around that. So we'll talk about pricing strategy, specifically, but we're very vigilant of the environment that we're in and we're going to act appropriately in that environment, and really try to conclude bar nonexistent they can to beget certain patients -- as many patients hold access to the drug as practicable over time. But they contemplate there's a longer runway in terms of reaching out to patients and life cycle management opportunities would certainly aid to amass us up to higher peak sales levels.

    Liisa Bayko -- JMP Securities -- Analyst

    Okay. Thank you very much for your comments. esteem it.

    A. Brian Davis -- Chief financial Officer

    Thanks Liisa.

    Operator

    Thank you. And I'm showing no further questions at this time. I'd like to revolve the convene back to Mr. Matthew Pauls for any closing remarks.

    Matthew Pauls -- President and Chief Executive Officer

    Thank you. In summary, these fourth quarter and complete year 2018 results underscore that their strategy, their assets, their people, their capital and their infrastructure well position us for continued success in 2019 and beyond. Thank you for joining today's convene and for your continued support.

    Operator

    Ladies and gentlemen, thank you for participating in today's conference. This does conclude today's program. You may bar nonexistent disconnect. Everyone hold a worthy day.

    Duration: 33 minutes

    Call participants:

    Lindsay Rocco -- Investor Relations

    Matthew Pauls -- President and Chief Executive Officer

    Fredric Cohen -- Chief Medical Officer

    A. Brian Davis -- Chief financial Officer

    Esther Hong -- Janney -- Analyst

    Nick Rubino -- Stifel -- Analyst

    Hartaj Singh -- Oppenheimer & Company -- Analyst

    Liisa Bayko -- JMP Securities -- Analyst

    More SBBP analysis

    Transcript powered by AlphaStreet

    This article is a transcript of this conference convene produced for The Motley Fool. While they strive for their fatuous Best, there may live errors, omissions, or inaccuracies in this transcript. As with bar nonexistent their articles, The Motley Fool does not assume any responsibility for your utilize of this content, and they strongly embolden you to conclude your own research, including listening to the convene yourself and reading the company's SEC filings. gladden perceive their Terms and Conditions for additional details, including their Obligatory Capitalized Disclaimers of Liability.

    Motley Fool Transcribers has no position in any of the stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.


    Nektar Therapeutics to Webcast Conference convene for Analysts and Investors at the 2019 ASCO-SITC Clinical Immuno-Oncology Symposium | killexams.com real questions and Pass4sure dumps

    SAN FRANCISCO, Feb. 25, 2019 /PRNewswire/ -- Nektar Therapeutics (NKTR) announced today that it will webcast an analyst and investor conference convene with lead investigator of the REVEAL study, Dr. Adi Diab, and company management on Friday, March 1, 2019 at 3:00 p.m. Pacific Time during the 2019 ASCO-SITC Clinical Immuno-Oncology Symposium. The event will result Friday's oral presentation by Dr. Diab of prefatory data from the ongoing dose-escalation stage of the reveal aspect 1/2 clinical study evaluating the combination of TLR agonist, NKTR-262, with a CD122-preferential IL-2 pathway agonist, bempegaldesleukin* (NKTR-214), in patients with locally advanced or metastatic solid tumors.

    Details on the Analyst Call:

    Date and Time: Friday, March 1, 2019 at 3:00 p.m. Pacific Time

    Dial-in: 877-881-2183 (toll-free) or 970-315-0453 (international)

    Passcode: 6970019

    The conference convene will include lead investigator on the reveal study, Dr. Adi Diab, coadjutant Professor of Melanoma Medical Oncology at The University of Texas MD Anderson Cancer Center. The webcast and slides for the conference convene can live accessed through a link that is posted on the Investors section of the Nektar website at https://ir.nektar.com/events-and-presentations/events. The event will furthermore live available for replay for two weeks on the company's website, www.nektar.com.

    Details on the Oral Presentation at ASCO-SITC:

    Abstract Title: "Phase Ib: prefatory clinical activity and immune activation for NKTR-262 [TLR 7/8 

    agonist] plus NKTR-214 [CD122-biased agonist] in patients (pts) with locally advanced or metastatic solid

    tumors (REVEAL aspect Ib/II Trial)"

    Abstract: #28

    Presenter: Dr. Adi Diab, MD Anderson Cancer Center

    Session: Oral Abstract Session B

    Date and Time: Friday, March 1, 2019, 1:00 p.m.-2:15 p.m. Pacific Time

    About NektarNektar Therapeutics is a research-based, development stage biopharmaceutical company whose mission is to ascertain and develop innovative medicines to address the unmet medical needs of patients. Their R&D pipeline of original investigational medicines includes treatments for cancer, auto-immune disease and inveterate pain. They leverage Nektar's proprietary and proven chemistry platform in the discovery and design of their original therapeutic candidates. Nektar is headquartered in San Francisco, California, with additional operations in Huntsville, Alabama and Hyderabad, India. Further information about the company and its drug development programs and capabilities may live establish online at www.nektar.com.

    * rINN (recommended International Nonproprietary Name)

     

    View original content:http://www.prnewswire.com/news-releases/nektar-therapeutics-to-webcast-conference-call-for-analysts-and-investors-at-the-2019-asco-sitc-clinical-immuno-oncology-symposium-300801596.html


    American Outdoor Brands Corporation® Third Quarter Fiscal 2019 financial Release and Conference convene Alert | killexams.com real questions and Pass4sure dumps

    SPRINGFIELD, Mass., Feb. 22, 2019 /PRNewswire/ -- American Outdoor Brands Corporation (nasdaq global select:AOBC) today announced that it plans to release its third quarter fiscal 2019 financial results on Thursday, March 7, 2019, after the nigh of the market. The complete text of the press release will live available on the American Outdoor Brands web site at www.aob.com under the Investor Relations section.

    The company will host a conference convene and webcast on March 7, 2019, to discuss its third quarter fiscal 2019 financial and operational results. Speakers on the conference convene will include James Debney, President and Chief Executive Officer, and Jeffrey D. Buchanan, Executive Vice President and Chief financial Officer. The conference convene may include forward-looking statements. The conference convene and webcast will commence at 5:00 p.m. Eastern Time (2:00 p.m. Pacific Time). Those interested in listening to the conference convene via telephone may convene directly at (844) 309-6568 and reference conference identification number 9683518. No RSVP is necessary. The conference convene audio webcast can furthermore live accessed live and for replay on the company's website at www.aob.com, under the Investor Relations section. The company will maintain an audio replay of this conference convene on its website for a era of time after the call. No other audio replay will live available.

    About American Outdoor Brands Corporation American Outdoor Brands Corporation (nasdaq global select:AOBC) is a provider of property products for shooting, hunting, and rugged outdoor enthusiasts in the global consumer and professional markets. The Company reports two segments: Firearms and Outdoor Products & Accessories. Firearms manufactures handgun long gun, and suppressor products sold under the Smith & Wesson®, M&P®, Thompson/Center Arms™, and Gemtech® brands, as well as provides forging, machining, and precision plastic injection molding services. AOB Outdoor Products & Accessories is the industry leading provider of shooting, reloading, gunsmithing, gun cleaning supplies, specialty tools and cutlery, and electro-optics products and technology for firearms. They produce innovative, top property products under the brands Caldwell®; Wheeler®; Tipton®; Frankford Arsenal®; Lockdown®; BOG®; Hooyman®; Smith & Wesson® Accessories; M&P® Accessories; Thompson/Center Arms™ Accessories; Schrade®; customary Timer®; Uncle Henry®; Imperial®; BUBBA®; UST®;  Lasergrips®, Laserguard®, LiNQ®, Lightguard®, Defender Series™, Rail Master®, and LaserLyte.  For more information on American Outdoor Brands Corporation, convene (844) 363-5386 or log on to www.aob.com.  

    Contacts:Liz Sharp, VP Investor RelationsAmerican Outdoor Brands Corporation(413) 747-6284lsharp@aob.com

    View original content to download multimedia:http://www.prnewswire.com/news-releases/american-outdoor-brands-corporation-third-quarter-fiscal-2019-financial-release-and-conference-call-alert-300800591.html

    SOURCE American Outdoor Brands Corporation

    Copyright (C) 2019 PR Newswire. bar nonexistent rights reserved



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