actual 000-448 questions and remedy answers! It justify the charge.
I had taken the 000-448 instruction from the killexams.com as that modified into a nice platform for the training and that had ultimately given me the fine degree of the steerage to collect the splendid scores inside the 000-448 select a glance atchecks. I simply loved the manner I got the topics completed within the exciting manner and through the succor of the identical; I had in the long rush had been given the detail on the line. It had made my guidance a obliging buy less complex and with the succor of the killexams.com I were capable of develop well within the existence.
No extra battle required to bypass 000-448 exam.
I passed this exam with killexams.com and feature these days received my 000-448 certificate. I did every my certifications with killexams.com, so I cant commemorate what its want to select an exam with/without it. But, the fact that I hold coming again for his or her bundles indicates that Im joyous with this exam solution. I clearly relish being able to workout on my pc, in theconsolation of my domestic, especially when the sizable majority of the questions acting at the exam are precisely the identical what you observed for your trying out engine at domestic. Manner to killexams.com, I got up to the professionalstage. I am now not positive whether or not or now not sick live shifting up any time fast, as I materialize to live joyous wherein i am. Thanks Killexams.
I do every my efforts on internet and discovered killexams 000-448 real question bank.
Its concise answers helped me to accomplish obliging marks noting every questions under the stipulated time in 000-448. Being an IT master, my abilities with respect are so forth need to live good. Not withstanding, proceeding with a customary employment with gigantic obligations, it was not simple for me to select a solid planning. At that point, I organize out about the generally organized question and admit aide of killexams.com dumps.
I feel very confident by preparing 000-448 real exam questions.
To become a 000-448 certified, i was in thrust to skip the 000-448 exam. I tried and failed closing 2 tries. Accidently, I had been given the killexams.com material through my cousin. I was very inspired with the material. I secured 89%. I am so happy that I scored above the margin label with out problem. The material is well formatted as well as enriched with crucial principles. I cerebrate it is the extremely obliging covet for the exam.
simply attempt those dumps and success is yours.
This killexams.com from helped me collect my 000-448 ally affirmation. Their materials are truly useful, and the exam simulator is simply incredible, it completely reproduces the exam. Topics are pellucid very easily using the killexams.com study material. The exam itself was unpredictable, so Im joyful I utilized killexams.com . Their packs spread every that I need, and I wont collect any unsavory shocks amid your exam. Thanx Guys.
WTF! questions believe been precisely the equal in exam that I prepared!
i bought 000-448 instruction % and passed the exam. No issues in any respect, the gross lot is exactly as they promise. smooth exam experience, no problems to record. thank you.
making ready 000-448 examination with is live counted modern some hours now.
ive been so feeble my entire course yet I recognise now that I needed to collect a bypass in my 000-448 and this will profile me current probably and sure im quick of radiance yet passing my tests and solved almost every questions in just 75 minutes with killexams.com dumps. more than one exquisite men cant deliver a exchange to planets manner however they can simply will let you realize whether you believe got been the principle fellow who knew the course to accomplish this and i need to live recognized in this world and profile my own specific imprint.
How to prepare for 000-448 exam?
This is my first time that I took this carrier. I sense very assured in 000-448 but. I do together my 000-448 the expend of questions and solutions with exam simulator softare through killexams.com crew.
Tips & tricks to certify 000-448 exam with towering scores.
I believe earned better rankings in 000-448 certification with the assist of rather cheap products. I were given 000-448 exam engine to cast off difficult requirements of this certification. I had sold 000-448 exam braindump to believe colourful grades inside the certification. It changed into precise choice because of the truth those products are designed in step with my brain-set. It helped me to collect study in fifteen days and after this short time I had scored suitable with the assist of those sensible merchandise consequently i am writing to discipline thanks to every of you to your exquisite services.
Can I find dumps Q & A of 000-448 exam?
killexams.com has pinnacle products for university students due to the truth the ones are designed for the ones students who are inquisitive about the training of 000-448 certification. It became exquisite selection because of the fact 000-448 exam engine has grotesque test contents which can live smooth to understand in brief time frame. I am grateful to the astonishing crewbecause this helped me in my profession improvement. It helped me to grasp a course to solution every essential questions to collect maximum markss. It changed into brilliant choice that made me fan of killexams. i believe decided to Come back one moretime.
newsIBM to purchase crimson Hat, a leading Java neighborhood Contributor
IBM announced on Sunday plans to purchase main enterprise open source application company and longtime Java neighborhood system (JCP) chief red Hat in a $34 billion inventory deal.
Described by means of massive Blue as IBM's most massive acquisition and probably the most gigantic tech acquisition of 2018, the deal represents "a landmark second for both groups and is an incredible step forward in IBM's ongoing focal point on excessive-cost company, the transformation of their portfolio, and their leadership in the emerging era of AI and cloud."
IBM and pink Hat talked about the deal, which has been accredited by their respective boards, is region to purple Hat shareholder and regulatory approval, and will live completed within the latter half of 2019.
speaking this morning with press and analysts on a conference name, Paul Cormier, red Hat's EVP and president of products and technologies, talked about the merger will back his company know its imaginative and prescient for its Linux and open supply choices.
"over the terminal 10 years or so, Linux has been the platform where most of the innovation in the commerce has been going on," Cormier spoke of. "We constructed a purposeful portfolio round Linux and open source tailor-made for the hybrid cloud ... however we're nonetheless a relatively petite enterprise. Their valued clientele are seeing open hybrid cloud because the simplest fashion to convey public cloud into their IT infrastructure, and because of their dimension they can not diagnosed the talents of that demand. IBM helps us deliver that fashion to one hundred seventy nations and accelerates their vision into the market."
IBM has long been a leading consumer and contributor to Linux, which undergirds crimson Hat's remedy products, together with the red Hat enterprise Linux (RHEL) OS.
On that identical conference name, Arvind Krishna, IBM's SVP of Hybrid Cloud, referred to this acquisition will profile his enterprise the world's leading hybrid cloud issuer. IBM's intention, he talked about, "is to win in hybrid cloud, and win on the foundation of open technologies, and in the cessation to give a know-how that makes life easier [for companies] with much less complexity and a future proof investment."
To a query concerning the knowledge repercussion of the acquisition on pink Hat-maintained open supply projects, similar to Fedora, Gnome, and CentOS, Cormier answered succinctly "None. No impact," he mentioned. "The day after they shut [the acquisition], I don't intend to accomplish anything distinct. For us, it should live enterprise as typical. whatever they had been going to accomplish for their roadmaps as a stand-on my own will continue. They must accomplish what's appropriate for the neighborhood upstream, their friends and their company."
both executives claimed that the leading roles the two organizations play in the JCP usually are not littered with the merger. IBM and crimson Hat are dynamic members of the Java group, however Raleigh, N.C.-primarily based purple Hat is likely one of the most lively contributors, and has been for decades.
"each IBM and purple Hat believe been potent voices in that group," Cormier mentioned, "and i suppose in order to continue. pink Hat will proceed to accomplish what's remedy for the red Hat portfolio, and that i would guess that IBM would accomplish the equal."
red Hat is, in reality, the greatest contributor to the OpenJDK next to Oracle. pink Hat executives believe served on the JCP executive Committee and as Java spec leads or skilled Working community individuals for more than 35 Java Specification Requests (JSRs). the primary Context and Dependency Injection spec (JSR 299), which become led by using JBoss Fellow Gavin King, had a astronomical outcome on Java EE 6. The company changed into likewise behind commerce JavaBeans (EJB) 3, JavaServer Faces, and the Java Persistence API. It collaborated on four JSRs for Java EE 7: Java API for RESTful web features 2.0 (JSR-339); Java Message service 2.0 (JSR-343); Java Server Faces 2.2 (JSR-344); and Java content Repository API (JSR-333).
red Hat additionally spearheaded two OpenJDK initiatives: Shenandoah (JEP 189), which aims to supply an extremely-low-pause-time rubbish Collector; and Thermostat , an instrumentation device for the Hotspot JVM.
Martijn Verburg, CEO of jClarity, co-organizer of the London JUG, and a member of the Java neighborhood manner (JCP) executive Committee, expects "a positive result" from the acquisition.
"IBM has truly shown crimson Hat-like characteristics when it comes to Java and Open source," Verburg stated in an electronic mail. "They've these days OpenSourced their J9 VM (Eclipse OpenJ9) in addition to their WebSphere utility Server (Open Liberty). They are likewise proper tier helps of Microprofile, Jakarta EE and crucially adopt OpenJDK.
Reza Rahman, SVP at AxonIQ, former Oracle Java developer evangelist, and co-founder of the Java EE Guardians, is "of two minds" on the acquisition.
"I totally select into account the company judgement in the back of this for both IBM and crimson Hat," he informed ADTmag. "here is unequivocally respectable for the shareholders and employees of both corporations. youngsters, the truth is that the influence for clients and the Java EE ecosystem may additionally now not always live so rosy. it will seemingly imply less alternatives for Java EE users and less market competitiveness. for example, it will not shock me if Websphere Liberty, Open Liberty, JBoss EAP, WildFly, and Thorntail now need to merge. i'm hoping smaller and more recent market entrants will fill in any aggressive gaps, as they should quiet in a suit pecuniary space."
"I likewise wish each the Java EE folks at IBM and pink Hat every the premiere as long term colleagues," he introduced. "with a bit of luck they could live able to profile this a pretty obliging result for Java EE."a different Java EE Guardian, Kito Mann, who is a principal advisor at Virtua Inc., sees a obvious synergy amongst Linux, Java, and cloud functions, but he worries about astronomical Blue.
"IBM's song list with acquisitions is questionable," he referred to in an e mail. "pink Hat has finished a tremendous job championing open source and building first rate items. however IBM has quite a lot of involvement with open supply, it live simply no longer at the equal level. My topic is that crimson Hat will collect absorbed into one or greater huge IBM product lines and then fade into mediocrity or irrelevance (remember Rational?)"
concerning the Java connection, Mann has some questions: "in terms of Java, does this imply pink Hat products will start delivery with the IBM Java VM?" he asked. "What about JBoss and WebSphere (Liberty)? What about the entire first-rate OSS products from crimson Hat/JBoss, and the company's drudgery subculture?"
JNBridge CTO and co-founder Wayne Citrin, likewise has a number of considerations concerning the merger. "My sentiment is that there's attending to live too tons concentration in the trade," he observed in an e mail, "and this would not help. red Hat appeared to live doing simply first-class and didn't need to merge, but I cannot weakness them for cashing in."
John has been overlaying the high-tech beat from Silicon Valley and the San Francisco Bay region for pretty much two decades. He serves as Editor-at-large for software evolution tendencies (www.ADTMag.com) and contributes always to Redmond journal, The know-how Horizons in education Journal, and Campus know-how. he is the author of greater than a dozen books, together with The everything reserve to gregarious Media; The every thing laptop ebook; Blobitecture: Waveform structure and Digital Design; John Chambers and the Cisco means; and Diablo: The legit approach ebook.
As a developer, I’m generally making an attempt to find IBM Cloud carrier circumstances that I’ve provisioned or that i used to live given access to over time. i am a member of distinctive agencies (three to live certain, presently containing 15+ areas) and that i’m having a tough time remembering through which arduous and space the service illustration I’d relish to access is discovered.
The IBM Cloud internet console and the IBM Cloud Developer tools CLI each most efficacious screen carrier cases for a sole Cloud Foundry firm/area combination, akin to ptitzler_org/dev as shown under.IBM Cloud internet console and IBM Cloud Developer tools CLI circumscribe service illustration views to a sole Cloud Foundry organization and space.
To locate a service instance, I hence deserve to iterate through every viable corporation/space combination (using the internet GUI or with the aid of working the applicable CLI commands) except the service instance of pastime is discovered. achievable, but inefficient.
Most commonly I’m going via this technique to retrieve the service credentials so that i can expend the provider case (for instance, an information provider relish Cloudant or an analytical provider relish Watson machine studying) from a pc or a stand-by myself app.accessing Cloudant service case credentials the expend of the cloud console.
I’ve at terminal taken the probability to streamline the procedure by means of making a Python computer application that gathers and visualizes Cloud Foundry catalog counsel for businesses, spaces and repair instances that a given IBMid or IBM Cloud consumer API key has entry to:IBM Cloud provider case list with filters for carrier forms, carrier plans and Cloud Foundry companies and areas.
To gather provider credentials, I now just should rush the app in a workstation, apply the favored filter(s) to find the provider illustration and click on a button to insert the selected credentials birthright into a mobilephone:candy. One click on inserts service credentials into a Python computing device cell for later consumption.
in case you’d want to provide this a are trying for your endemic Jupyter environment or within the cloud, download the pc, add your IBM Cloud user API key or IBMid credentials and rush every cells. The app displays in the remaining mobilephone. No counsel is permanently kept or shared.
word that this application at the instant most efficacious collects suggestions about features which are managed by means of Cloud Foundry, but doesn't bring together counsel about functions which are managed through IAM.Cloud Foundry-managed and IAM-managed provider instances are displayed one after the other in the IBM Cloud internet console.
To learn greater about the software, read on.in regards to the software
The Python 2.7/3.x software comprises of two classes: a Cloud Foundry carrier information collector and a visualizer, which might live invoked via the Browser class:Invoking the Cloud Foundry service instance browser app. Configuration
The utility requires IBM Cloud credentials — which can live either an IBMid and password or an IBM Cloud user API key — to fetch counsel in regards to the components that the offered credentials believe entry to. if you prefer to not store the credentials in pellucid text you can comfortably seize the input interactively, relish so:import getpassibm_cloud_user_api_token = getpass.getpass()... statistics assortment
The records Collector gathers the necessary suggestions from the IBM Cloud catalog the expend of the Cloud Foundry comfort API and outlets it in a Pandas DataFrame. dissimilar calls are made to load study up tips, which allows the app to screen names in its set of interior identifiers. commemorate that no sensitive tips (a.ok.a., the credentials) is gathered throughout the collection.
If desired, that you could access and explore the DataFrame by means of calling the Browser type’s getPandasDataFrame() components. I are inclined to expend PixieDust to investigate cross-check the content of DataFrames , a nifty Python productiveness device their Developer Advocacy group has developed, because it gives interactive filtering and visualization.Filter the collected records, customise the monitor and even render it graphically by using changing the visualization options.
I’ve decided to preserve the facts assortment code shatter away the visualization code. It provides two benefits:
The Visualizer is applied using PixieApps, an open-source framework that makes expend of Python, HTML and CSS to construct interactive visualizations for Python notebooks. It’s pretty primary but gets the job carried out: it shows a group of context-delicate filters and the list of carrier circumstances that meet the filter situations:simplest companies by which Cloudant Lite device cases exist are protected in the filter.
simplest after a person selects a selected provider case (with the aid of clicking the View Credentials button) is a request despatched to IBM Cloud using the Cloud Foundry API, retrieving the credentials.
A person can then select to insert credentials into a brand current mobilephone, which generates a Python dictionary. With the credentials in vicinity, access to to provider instance is only a piece of code away:elementary credentials consumption situation. critical cred(s)
received some ideas to enrich this app or need to build your personal spin-off? every you should collect begun is during this Github Repository.
notwithstanding no longer a prevailing class of cyber assaults, superior persistent threats (APTs) are truly essentially the most devastating ones. similar to a sudden volcano eruption that’s been slowly surging underneath, an ATP might likewise reside invisible for a lot of months but finally outcome in censorious monetary harm, ruining businesses’ attractiveness and even lead to human victims as it happened after the scandalous Ashley Madison statistics breach.
The annual cyber risk report M-trends 2016 by Mandiant pointed out that the habitual number of days in 2015 during which organizations were compromised earlier than they discovered the transgression (or had been notified concerning the breach) turned into 146. To profile issues even worse, protection consultants reveal the majority of APTs accidentally, which potential that APTs’ actual lifecycle is limited handiest by means of the vigour of vigilance. So is the battle with APTs in fact a depend of luck? Or is there anything to detect them earlier than they damage a company’s assets?advertisement Why are natural tools no respectable?
With APTs, you might likewise feel that corporations are too a worthy deal lax about their protection and select insufficient security measures. in fact, targeted entities constantly undertake the entire latitude of safety equipment from common firewalls and antiviruses to refined anti-malware items. The problem is that these traditional tools aren’t able to stand up to an APT attack, leaving a pretty obliging number of blind spots in an commercial enterprise’s infrastructure.
for instance, firewalls as an essential a allotment of network safety can nearby needless ports and obstruct unsolicited incoming community site visitors. Their superior models can even partially present protection to against DDoS assaults. however they in reality can’t determine malicious clients, dissect packets containing malware and obviously they can not deal with attacks that don’t disappear through them. because of natural firewalls’ constrained performance, most businesses supplement them with intrusion prevention techniques (IPS) that permit to examine network traffic flows, become sensible of and forestall vulnerability exploits. however, IPS likewise believe their limitations as they are helpless in opposition t customer-aspect utility assaults.
additionally, managing an array of protection tools is difficult and costly, as you need to purchase numerous software licenses and rent experts to select faith of each and every inevitable piece of software. It’s likewise impossible to manually correlate records from dissimilar techniques in order to determine and reply to proliferating attacks. And, eventually, scattered options can't profile sure a 360° view of a corporation’s IT ambiance, which eventually consequences in loopholes that allow hackers in.
on the identical time, nowadays’s security application market presents superior protection guidance and event administration (SIEM) solutions that are capable of exchange multiple scattered options. despite the fact that now not regarded because the top-quality treatment against APTs, SIEM techniques might back protection officers at distinctive degrees of an assault.getting to know from being training: The case of Carbanak assaults
To collect every armed for feasible attacks, it’s constructive to investigate outdated blunders. in the background of safety breaches, APTs believe a ’music listing’ of calamitous intrusions. among them there are a chain of assaults with the aid of the Carbanak neighborhood that targeted greater than 100 banks and other monetary institutions in 30 nations (the U.S. named the 2d greatest target), which made it some of the biggest pecuniary institution thefts ever.
all started out in August 2013, this subtle hacking gang turned into first publicly disclosed only in 2015 when the gross profit already reached $1 billion. To live disregarded and learn every bank inner out, attackers used an entire latitude of strategies from spear phishing to quiescent watch, stealing money in modest batches. The theft become printed by chance, after inspecting one ATM’s atypical behavior. besides the fact that children, disclosure didn’t halt the Carbanak hackers from their shady affairs: a current chain of attacks were already registered in 2016. This time, the group aims to double down the stale trap. but what if victims had a first-class-tuned SIEM answer?
as the banks were unprepared for these attacks and had no vital solutions in location to realize the APTs, they decided to select this case as an case and illustrate how a first-rate-tuned SIEM answer, comparable to IBM QRadar, might assist to prove the Carbanak superior persistent threats.Malware an infection
in accordance with the publicly purchasable particulars of the assault, the hackers bought access to pecuniary institution employees’ computer systems through opportunistic malware. IBM safety QRadar QFlow Collector could pinpoint a malware infection by using making inevitable constant monitoring of the traffic getting in and out of a company. The implement tactics classes and circulate counsel from external sources in such codecs as QFlow, NetFlow, SFlow, JFlow and periods from Packeteer, which allows for to baseline community site visitors and do in force anomaly suggestions, in addition to to build up selected correlation rules to notice the following:
as soon as the attackers received entry to personnel’ computers, they begun a large spear phishing campaign that was very challenging to establish. certainly, a SIEM admit can rarely distinguish an contaminated email message originating from a legitimate electronic mail account (a computing device with malware) from a legitimate email. despite the fact, if the e mail server is linked to a SIEM solution as a log source, it’s workable to realize here abnormalities:
The advanced correlation with physical protection controls additionally makes it workable for detection of mailouts from users before their assess-in via a actual protection gate.Privilege escalation and deeper reconnaissance
Systematic spare phishing coupled with malware an infection allowed the group to continue their attack via privilege escalation and deeper reconnaissance that are natural for every APTs.
Privilege escalation can live monitored with a first-rate-tuned SIEM admit with birthright here:
In any such situation, any user and not using a Admin duty logging in with administrative privileges would trigger an alert in a SIEM solution. in addition, most of SIEM solutions include out-of-the-box reconnaissance detection correlation rules that will likewise live high-quality-tuned to lower false-positives. In their case, a deeper reconnaissance originating from an internal company community may live identified if firewalls had been sending entry logs to a SIEM answer.Latent watch
To more desirable select note the internal methods, the hackers assigned operators to drudgery with video- and display-catch feeds grabbed and transmitted to the attackers with the previously injected malware.
The ordinary site visitors analysis in line with anomaly rules would determine video and screen taking pictures actions given that video translation produces loads of site visitors that can live caught through IBM security QRadar QFlow Collector.an infection of computer systems connected to ATMs
The Carbanak gang efficiently infected computers connected to ATMs with a purpose to profile the machines dispense cash. In case if compromised administrative money owed were used to unfold infection, a SIEM admit could live able to alert the security personnel concerning the following:
moreover, an superior correlation with identity and entry management options and Ticketing programs would allow to notice instances when an admin user was logging to the gadget with no acceptable ticket or IAM allowance.Compromise of inner databases and creation of fraudulent money owed
during the attacks, hackers manipulated Oracle databases to open payment or debit card money owed on the identical pecuniary institution or to transfer funds between money owed the expend of the online banking equipment. continuously, every activity related to developing current debts may quiet walk through a validation system. reckoning on this type of process and equipment used for validation, this counsel may live integrated with a SIEM solution to alert on surprising account advent. If there’s no such validation in location, every current account advent can live alerted and investigated by a safety analyst.
A SIEM advisor may succor a pecuniary institution to collect stories on business-crucial statistics change by doing birthright here:
To live able to circulation large quantities of cash into controlled accounts, the attackers abused the Society for international Interbank economic Telecommunication gadget. A neatly-configured SIEM solution could profile sure a constant monitoring of every crucial fiscal functions. If a particular utility weren’t supported through QRadar out-of-the-container, appropriate parsing, mapping and categorization can live developed. once customized information is properly normalized, a SIEM admit would live in a position to realize abnormal funds transfers with anomaly correlation rules, if here are proper:
The case we’ve just analyzed proves that agencies don't appear to live helpless in their combat in opposition t APTs. it can sound strange, but at the same time as sophisticated as they are, APTs believe their weakness hiding within the letter “P.” Persistence, which is probably the most problematic to select faith of, truly potential that attackers disappear away loads of traces at some point of their attacks. consequently security administrators smartly-armed with a principal SIEM admit believe multiple touchpoints to detect intruders and forestall them before their unlawful actions occasions theatrical statistics and funds losses.
This submit become backed via ScienceSoft. The content turned into created via Dmitry Nikalayenia, SIEM fork Coordinator for ScienceSoft and a visitor contributor to Gigaom.
Obviously it is arduous assignment to pick solid certification questions/answers assets concerning review, reputation and validity since individuals collect sham because of picking incorrectly benefit. Killexams.com ensure to serve its customers best to its assets concerning exam dumps update and validity. The vast majority of other's sham report objection customers Come to us for the brain dumps and pass their exams cheerfully and effectively. They never trade off on their review, reputation and character because killexams review, killexams reputation and killexams customer conviction is vital to us. Uniquely they deal with killexams.com review, killexams.com reputation, killexams.com sham report grievance, killexams.com trust, killexams.com validity, killexams.com report and killexams.com scam. In the event that you see any mistaken report posted by their rivals with the cognomen killexams sham report grievance web, killexams.com sham report, killexams.com scam, killexams.com dissension or something relish this, simply remember there are constantly terrible individuals harming reputation of obliging administrations because of their advantages. There are a worthy many fulfilled clients that pass their exams utilizing killexams.com brain dumps, killexams PDF questions, killexams hone questions, killexams exam simulator. Visit Killexams.com, their specimen questions and test brain dumps, their exam simulator and you will realize that killexams.com is the best brain dumps site.
DEV-401 rehearse questions | HP2-T11 free pdf | 1Z0-052 dumps questions | ACE questions and answers | JN0-647 real questions | A2150-006 rehearse questions | A2090-544 study guide | HP2-K30 brain dumps | COG-135 exam prep | MB3-209 dump | C9560-659 free pdf download | CGEIT bootcamp | 4A0-M01 study guide | 6207-1 pdf download | LOT-925 exam prep | 1Z0-430 test prep | HDPCD braindumps | CCN examcollection | 000-914 exam questions | GE0-807 cheat sheets |
Once you memorize these 000-448 , you will collect 100% marks.
killexams.com is a dependable and trustworthy platform who provides 000-448 exam questions with 100% success guarantee. You need to rehearse questions for one day at least to score well in the exam. Your real journey to success in 000-448 exam, actually starts with killexams.com exam rehearse questions that is the excellent and verified source of your targeted position.
Are you looking for Pass4sure IBM 000-448 Dumps containing real exams questions and answers for the IBM Content Collector (ICC) v2.2 Exam prep? They provide most updated and character source of 000-448 Dumps that is http://killexams.com/pass4sure/exam-detail/000-448. They believe compiled a database of 000-448 Dumps questions from actual exams in order to let you prepare and pass 000-448 exam on the first attempt.
killexams.com Huge Discount Coupons and Promo Codes are as under;
WC2017 : 60% Discount Coupon for every exams on website
PROF17 : 10% Discount Coupon for Orders greater than $69
DEAL17 : 15% Discount Coupon for Orders greater than $99
DECSPECIAL : 10% Special Discount Coupon for every Orders
The best course to collect achievement in the IBM 000-448 exam is that you ought to acquire dependable preparatory materials. They guarantee that killexams.com is the most direct pathway toward Implementing IBM IBM Content Collector (ICC) v2.2 exam. You will live triumphant with plenary certainty. You can see free questions at killexams.com before you purchase the 000-448 exam items. Their reenacted tests are the same As the real exam design. The questions and answers made by the ensured experts. They give you the experience of stepping through the real exam. 100% guarantee to pass the 000-448 actual test.
killexams.com IBM Certification study guides are setup by IT experts. Heaps of understudies believe been griping that an extreme number of questions in such a large number of rehearse exams and study aides, and they are simply worn out to tolerate the cost of any more. Seeing killexams.com specialists drudgery out this thorough adaptation while quiet guarantee that every the information is secured after profound research and investigation. Everything is to profile console for applicants on their street to certification.
We believe Tested and Approved 000-448 Exams. killexams.com gives the most exact and latest IT exam materials which nearly accommodate every information focuses. With the lead of their 000-448 study materials, you don't need to squander your haphazard on perusing greater allotment of reference books and simply need to scorch through 10-20 hours to ace their 000-448 real questions and answers. What's more, they give you PDF Version and Software Version exam questions and answers. For Software Version materials, Its offered to give the hopefuls recreate the IBM 000-448 exam in a real domain.
We give free update. Inside legitimacy period, if 000-448 brain dumps that you believe bought updated, they will illuminate you by email to download latest rendition of . On the off haphazard that you don't pass your IBM IBM Content Collector (ICC) v2.2 exam, They will give you plenary refund. You believe to dispatch the verified duplicate of your 000-448 exam report card to us. after affirming, they will give you plenary REFUND.
killexams.com Huge Discount Coupons and Promo Codes are as under;
WC2017: 60% Discount Coupon for every exams on website
PROF17: 10% Discount Coupon for Orders greater than $69
DEAL17: 15% Discount Coupon for Orders greater than $99
DECSPECIAL: 10% Special Discount Coupon for every Orders
if you collect ready for the IBM 000-448 exam utilizing their testing engine. It is anything but difficult to prevail for every certifications in the first attempt. You don't need to manage every dumps or any free deluge/rapidshare every stuff. They present free demo of every Certification Dumps. You can study at the interface, question character and ease of expend of their rehearse exams before you select to purchase.
000-448 Practice Test | 000-448 examcollection | 000-448 VCE | 000-448 study guide | 000-448 practice exam | 000-448 cram
Killexams C2010-573 test prep | Killexams HP2-T14 braindumps | Killexams HP0-J54 questions and answers | Killexams 920-130 study guide | Killexams 1Z0-567 dumps questions | Killexams 156-815 mock exam | Killexams LOT-923 free pdf | Killexams 000-M60 sample test | Killexams HP0-812 dumps | Killexams M2180-716 study guide | Killexams HP0-A21 test prep | Killexams 117-202 rehearse questions | Killexams 000-430 free pdf download | Killexams S90-20A real questions | Killexams 70-569-CSharp bootcamp | Killexams 000-780 cheat sheets | Killexams C2040-924 dump | Killexams C2180-275 rehearse exam | Killexams MB3-208 test questions | Killexams 1Z0-338 brain dumps |
Killexams 117-101 braindumps | Killexams 000-783 rehearse questions | Killexams C2020-002 test prep | Killexams 000-M608 rehearse exam | Killexams 1Z0-459 braindumps | Killexams HP2-K22 mock exam | Killexams GD0-100 real questions | Killexams IC3-3 real questions | Killexams 250-300 cram | Killexams HAT-450 free pdf download | Killexams 700-265 pdf download | Killexams 1Z0-899 study guide | Killexams 000-108 dumps questions | Killexams HP2-N41 questions and answers | Killexams LOT-928 test prep | Killexams 000-834 test questions | Killexams JN0-680 study guide | Killexams PK0-004 brain dumps | Killexams 4A0-M01 free pdf | Killexams 250-512 questions answers |
Surfline, the world's leading action sports website, today announced it has accepted a strategic round of financing from prominent Internet pioneer, Kevin O'Connor, who will likewise been joining the Surfline board of directors.
Kevin was the co-founder, CEO and Chairman of DoubleClick, Inc. (NASDAQ: DCLK), the leading provider of ad serving technology on the Internet. DoubleClick was recently acquired by Google for over $3 billion. In addition, Kevin has helped launch numerous leading software entities, including ICC and Internet Security Systems (NASDAQ: ISSX) -- a commerce that was sold to IBM in 2006 for $1.3 billion. Kevin has likewise been an investor and advisor to companies relish 1800flowers.com and Hotjobs, which was acquired by Yahoo in 2002.
"We study forward to Kevin's involvement in helping us grow Surfline across the globe," said Chairman Jeff Berg. "Kevin's skill sets with Internet businesses are matched by his fire as a surfer and Surfline Premium Member. This opportunistic round of financing, along with Kevin's capabilities and interests, will allow us to invest more aggressively in a number of initiatives that will profile their sites more functional and enjoyable for surfers, ocean enthusiasts and others worldwide."
ABOUT SURFLINESurfline/Wavetrak Inc. is the world's leading collection of water enthusiast websites, every of which combine proprietary conditions-reporting and forecasting with timely news, information and entertainment. The sites are aimed at the core of each sport, yet they include content that appeals to a broader lifestyle audience as well. As a group, Surfline websites are visited are by over 1.5 million unique people each month.
This article breaks down the best OSINT tools, techniques, resources and websites available online for every stage of intelligence gathering process. From background reading, to organising your research and getting the best out of search engines, Intelligence Fusion has created the ultimate list of open source intelligence tools.
We’ll cover the following;
Open source intelligence, or OSINT, is the collection and analysis of information that is gathered from public, or open, sources.The Best OSINT Websites for Background Reading
This is a platform used to share papers, monitor their impact, and succeed the research in a particular field. Academia.edu currently has over 21 million papers.
2. CORE (COnnecting REpositories)
CORE promotes free and unrestricted access to research outputs from repositories and journals worldwide. The public can search through a collection of over 125 millions of harvested research outputs which can live downloaded free of charge.
3. Library of Congress
The Library of Congress is the largest library in the world, with millions of books, recordings, photographs, newspapers, maps and manuscripts in its collections.
4. Open knowledge Maps
Open knowledge Maps presents you with a topical overview of your search term. It’s based on the 100 most pertinent documents for your search term, which allows you to easily identify useful, pertinent information.
WolframAlpha is an online service that answers factual queries directly by computing the admit from externally sourced “curated data”, unlike a search engine that provides a list of documents or web pages that might accommodate the admit the searcher is looking for.
BASE is one of the world’s most voluminous search engines especially for academic web resources. ground provides more than 120 million documents from more than 6,000 sources. You can access the plenary texts of about 60% of the indexed documents for free.
7. Google Scholar
Google Scholar is a freely accessible web search engine that indexes the plenary text or metadata of scholarly literature across an array of publishing formats and disciplines.
8. Disputed Territories
This map identifies the locations and territories that are claimed by more than one country or occupying force.OSINT Techniques to Organise your Thoughts
1. Microsoft OneNote
Microsoft OneNote is a free-form information gathering and multi-user collaboration. It gathers users’ notes, drawings, screen clippings and audio commentaries and allows your OSINT resources to live easily shared amongst other users online.Setting up Automated Alerts using OSINT Tools
1. Google Alerts
Google Alerts is a content change detection and notification service that can live used as an open source intelligence tool. It will dispatch emails to you when it finds current results matching your specified search term.
2. Talkwalker Alerts
Talkwalker is an alternative free alert system to Google Alerts that offers a higher flat of customisation on alerts and notifications. Talkwalker can likewise monitor gregarious media mentions of your specified search term.OSINT Tools for Social Media
1. search A Tweet
Seekatweet is designed to succor you find pertinent tweets in a specific location. You can expend their tailored filtering as an OSINT implement to find Tweets near you or anywhere else in the world.
2. One Million Tweet Map
The one million tweet map is a gregarious media implement that you can expend to visualise tweets and aggregated Twitter data in a world map. It can live useful when conduction real-time OSINT investigations.
Tweepler is a real time map of tweets coming from various locations. The tweets shown on the map are only the fresh tweets. They are displayed as soon as received. No tweet location is older than a fraction of a minute.
Hashatit.com is a gregarious search engine for hashtags. You can search tags across every gregarious media platforms, bringing everything pertinent to your OSINT research to one set in real time.
An advanced Instagram search engine, Mulpix makes searching Instagram as an OSINT technique even easier through the leverage of searching via multiple hashtags.
Picodash is another Instagram search engine OSINT implement to succor you to search and analyse Instagram content by location and hashtags.
Echosec is a location-based gregarious media geofencing platform that analyses data in real-time to back retail, journalists, marketers and security teams as an open source intelligence tool.
TweetDeck is a gregarious media dashboard application for management of Twitter accounts. OSINT analysts can create live feeds of tweets to monitor specified hashtags, handles or mentions.OSINT Techniques: Getting the Best out of Search Engines
Carrot² is an open source search results clustering engine. It can automatically cluster petite collections of documents, for case search results or document abstracts, into thematic categories
Newslookup.com is a intelligence search engine, intelligence headline, intelligence feed and intelligence services provider that crawls several thousand intelligence media sites providing time based live rush down of headlines by region, topic or person.
Cluuz is a search engine that can live used as a really useful OSINT tool. Cluuz shows not only links to related pages, but likewise entities and images that are extracted from within the search results. In addition to the results, Cluuz displays a tag cloud of the most pertinent entities extracted from returned results.Platforms and Dashboards for Open Source Intelligence
HealthMap brings together disparate data sources to achieve a unified and comprehensive view of the current global situation of infectious diseases.
2. Investigative Database
The Investigative Database allows open source analysts to browse their global index of public registries for companies, land registries and courts as well as search millions of documents and datasets, from public sources, leaks and investigations.
3. IBM Watson intelligence Explorer
The IBM Watson intelligence Explorer automatically constructs a intelligence information network and presents large volumes of intelligence results in an understandable fashion.
4. Human Trafficking Search
HTS produces a weekly blog, publishes research, and hosts a global resource database on human trafficking and modern-day slavery.
5. Marine Traffic
MarineTraffic is a provider of ship tracking and maritime intelligence. Monitoring vessel movements to build a ground of data gathered from their network of coastal AIS-receiving stations, supplemented by satellite receivers.
Iris is an application developed by the World Customs Organisation that monitors open source information and presents this information in a graphic-style world map in real-time.
7. ICC Live Piracy Report
This live map from ICC shows every of the piracy and armed robbery incidents reported to IMB Piracy Reporting Centre.
ACLED is a realtime data and analysis source on political violence and protest. As an OSINT tool, analysts and researched can expend ACLED for the latest dependable information on current fight and disorder patterns.OSINT Websites for Online News Media
NewsNow aims to live the world’s most accurate and comprehensive world intelligence aggregator, bringing you the latest global current affairs headlines
AllYouCanRead.com is the largest database of magazines and newspapers on the Internet, with listings for about 25,000 magazines, newspapers and top intelligence sites from every over the world.
3. Newspaper Map
Newspaper map is a free webapp that helps you find over 10,000 of the world’s online newspapers, and in many cases collect to their Google translations in one click.
4. Distill Web Monitor
Monitor webpage or feed for changes asn an open source intelligence tool. Distill runs in your browser to check monitored pages for changes and can dispatch you instant alerts via SMS or email as soon as a change is detected.
Feedly is a intelligence aggregator application that can live used to compiles intelligence feeds from a variety of OSINT websites, online sources and allows the you to customise and share with others users online.Other Useful OSINT Tools
Additional tools that can live used as allotment of an OSINT framework can live organize below.
As allotment of their open source intelligence course, they provide extensive training on the most efficacious course to expend these OSINT tools as well as an impressive and diverse scope of additional modules, every built using real-life experiences from their ex-military and intelligence expert team.
1. IntelTechniques and Image Search
5. course Back Machine
6. Transparency International
8. Naval Open Source Intelligence
10. Relief Web
12. Police Sites
13. CIA Factbook
14. FBI Vault
15. OSAC Report
16. Global Terrorism Database
Intelligence Fusion uses these sources, teamed with military-grade processes and structure to enable a current course of thinking, encouraging analysts to adapt alternative mindsets to better discover, evaluate and understand threats of every kind.
Our OSINT training course can live adapted to clients’ requirements and tailored to meet bespoke requests. They believe the capacity to conduct countenance to countenance training, across the globe, or alternatively, they can likewise deliver the open source ntelligence course remotely.
If you’d relish further insight into what their training programme consists of, you can download a selection of slides from their benchmark training modules by clicking here.
BACKGROUND AND PURPOSE: Intervertebral disk biochemical composition could live accessed in vivo by T1ρ and T2 relaxometry. They organize no studies in the literature comparing different segmentation methods for data extraction using these techniques. Their direct was to compare different manual segmentation methods used to extract T1ρ and T2 relaxation times of intervertebral disks from MR imaging. Seven different methods of partial-disk segmentation techniques were compared with whole-disk segmentation as the reference standard.
MATERIALS AND METHODS: Sagittal T1ρ and T2 maps were generated by using a 1.5T MR imaging scanner in 57 asymptomatic volunteers 20–40 years of age. Two hundred eighty-five lumbar disks were separated into 2 groups: nondegenerated disk (Pfirrmann I and II) and degenerated disk (Pfirrmann III and IV). In whole-disk segmentation, the disk was segmented in its entirety on every sections. Partial-disk segmentation methods included segmentation of the disk into 6, 5, 4, 3, and 1 sagittal sections. Circular ROIs positioned in the nucleus pulposus and annulus fibrosus were likewise used to extract T1ρ and T2, and data were compared with whole-disk segmentation
RESULTS: In the nondegenerated group, segmentation of ≥5 sagittal sections showed no statistical divergence with whole-disk segmentation. every the remaining partial-disk segmentation methods and circular ROIs showed different results from whole-disk segmentation (P < .001). In the degenerated disk group, every methods were statistically similar to whole-disk segmentation. every partial-segmentation methods, including circular ROIs, showed stalwart linear correlation with whole-disk segmentation in both the degenerated and nondegenerated disk groups.
CONCLUSIONS: Manual segmentation showed stalwart reproducibility for T1ρ and T2 and stalwart linear correlation between partial- and whole-disk segmentation. Absolute T1ρ and T2 values extracted from different segmentation techniques were statistically different in disks with Pfirrmann grades I and II.ABBREVIATIONS: AAF anterior annulus fibrosus AF annulus fibrosus CROI circular ROIs ICC intraclass correlation coefficient NP nucleus pulposus PAF posterior annulus fibrosus PDS partial-disk segmentation WDS whole-disk segmentation
MR imaging is considered the best noninvasive fashion to study intervertebral disks. MR imaging allows the visualization of clearly different anatomic disk subregions, including the nucleus pulposus (NP) and the annulus fibrosus (AF).1,2 However, routine clinical images provide a qualitative or semiquantitative assessment made by an expert.3 The need for a better understanding of physiologic and pathologic processes in the disk led to the application of quantitative techniques in MR imaging such as T1ρ and T2 mapping.3,4
For the extraction of quantitative data from a given region of interest, it is necessary to discharge segmentation procedures that involve selecting the region to live analyzed.5 This segmentation can live manual, semiautomatic, or automatic. In studies assessing the lumbar intervertebral disk composition, different authors used different methods to discharge disk segmentation with subsequent data extraction. The most common fashion in the literature with respect to T1ρ and T2 is to acquire petite regions of interest that are anatomically based.6⇓⇓–9 Authors believe used benchmark ROIs, delineating subregions within the intervertebral disk to extract quantitative data specifically from the NP and AF.6,7 Additional intermediate ROIs on boundaries between the nucleus and annulus believe likewise been used.8,9 In the latter, intermediate ROIs were implemented to compensate for the increased steps for segmentation in each image. These studies analyzed a limited number of MR imaging sections. The segmentation using a few MR imaging sections and regional ROIs allows the extraction of data more quickly than segmenting the gross intervertebral disk. Other authors chose to discharge the segmentation of the disk as a whole, with the region of interest covering the NP and AF simultaneously.10,11 The expend of segmentation of only the central MR imaging sagittal section to extract quantitative data from the intervertebral disk is likewise very common in the literature.12,13
The intervertebral disk structure is nonuniform with differences in hydration and collagen content between NP and AF. Therefore, the extraction of different T1ρ and T2 relaxation times may live expected depending on the segmentation fashion used.10,14 Despite the potential instant of using different segmentation methods in the evaluation of the intervertebral disk composition, they believe not organize studies comparing the accuracy, reliability, and reproducibility of the results generated by different segmentation methods. Their hypothesis is that partial segmentation of intervertebral disks, especially through benchmark geometric regional ROIs, will result in the extraction of different T1ρ and T2 relaxation times compared with plenary segmentation.Materials and Methods Population Sample
This study was approved by the institutional review board. The volunteers were recruited through institutional review board–approved local advertisement and were selected on the basis of the inclusion criteria. They recruited 57 asymptomatic adults (25 men and 32 women), with a add up to age of 26.54 ± 5.0 years (range, 20–40 years); add up to height, 1.69 ± 0.08 m (1.53–1.90 m); add up to weight, 67.52 ± 13.85 kg (range, 46.5–105 kg); and add up to body mass index, 23.5 ± 3.4 kg/m2 (range, 15.9–30.3 kg/m2). The inclusion criteria for the volunteers were the following: 20–40 years of age with an Oswestry Dysfunction Index score <10. Volunteers with persistent low back stitch for at least 6 months; an Oswestry Dysfunction Index score >10; or previous spinal pathology, significant scoliosis, or surgery were excluded from the study.
All 5 lumbar disks of the 57 volunteers were studied; therefore, they evaluated 285 disks. The intervertebral disks were graded according to the Pfirrmann et al classification.14 After classification by the Pfirrmann grading system, they divided the intervertebral disks into 2 subgroups: nondegenerated (grades I and II) = 224 disks and degenerated (grades III and IV) = 61 disks. In their sample, they organize no grade V intervertebral disks according to the Pfirrmann et al classification.MR Imaging
All MR imaging examinations were performed by using a 1.5T scanner (Achieva; Philips Healthcare, Best, the Netherlands). They used a 16-channel spine coil (SENSE-SPINE; Philips). Volunteers were kept quiet in a supine position with the lower limbs extended and relaxed. The study protocol included a 2D swiftly spin-echo sequence with the following characteristics: orientation = sagittal, FOV = 22 × 22 cm, thickness = 4 mm, number of sections = 16, matrix = 256 × 256 and no intersection gap. For the segmentation process, they acquired a T2-weighted sagittal sequence, with TE = 120 ms and TR = 3900 ms. Spin-echo sequences were acquired to generate quantitative T1ρ and T2 maps. They used the following parameters—T2 multiecho sequence: TE = 20/40/60/80/100/120/140/160 ms and TR = 3000 ms; T1ρ multilocker times sequence: TE = 20 ms, TR = 2000 ms, Tlock = 2/10/20/40/60 ms. The total MR imaging acquisition time was 13 minutes.Image Evaluation
The panoply software (McConell Brain Imaging Center, Montreal, Quebec, Canada) was used for image analysis and segmentation. The segmentation process was performed on the sagittal plane according to the illustrations in Figs 1 and 2. The segmentation of 285 disks was performed by 2 independent and blinded observers, taking faith not to include regions of subchondral bone. They were previously trained for 2 months in manual spinal MR imaging segmentation and were supervised by a senior radiologist with 15 years' experience in musculoskeletal radiology and spine MR imaging. First, plenary manual segmentation of the gross intervertebral disk, encompassing NP and AF, for each disk in every 12 sections was performed for every lumbar disks of each volunteer (whole-disk segmentation [WDS]). Partial-disk segmentation (PDS) methods were performed by using 6 different techniques according to the illustration in Fig 1 by using the following: 6 sections (PDS-6), 5 sections (PDS-5A and PDS-5B), 4 sections (PDS-4), 3 sections (PDS-3), and only 1 central section (PDS-1). Extraction of T1ρ and T2 relaxation times was likewise performed by using 3 circular ROIs (CROI) placed on the NP, anterior annulus fibrosus (AAF), and posterior annulus fibrosus (PAF) by using 3 discrete sagittal sections as shown in Fig 2. The most central region of the NP was marked by using a region of interest with an region of 26.77 mm2. This region was labeled regardless of the presence or absence of a nuclear cleft. ROIs with 12.75 mm2 each were used in the regions of AAF and PAF. They placed ROIs on the most anterior and posterior regions of the annulus, avoiding selecting the transition regions between the AF and NP.Fig 1.
On the left is a sagittal T2-weighted image representing the segmented region of the intervertebral disk. On the birthright is the number of sections used in partial segmentation methods. A, Whole-disk segmentation. B, Partial-disk segmentation using 6 sections (PDS-6). C, Partial-disk segmentations using 5 sections, fashion A (PDS-5A). D, Partial disk segmentation using 5 sections, fashion B (PDS-5B). E, Partial-disk segmentation using 4 sections (PDS-4). F, Partial disk segmentation using 3 sections (PDS-3). G, Partial-disk segmentation using 1 central section (PDS-1).Fig 2.
A, The CROI subregions are indicated in a T2-weighted image in the sagittal plane of a volunteer: blue for the nucleus pulposus, red for the anterior annulus fibrosus, and yellow for the posterior annulus fibrosus. B, Axial image in which the CROI fashion was used.
The main researcher was the first observer, liable for the segmentation of every 285 lumbar disks. One hundred disks were randomly selected for intra- and interobserver reproducibility analysis, 50 from the degenerated group and 50 from the nondegenerated group. These disks were segmented a second time by the first and second observer with an interval of 2 months after the first segmentation.Statistical Analysis
The analysis of intra- and interobserver variability was performed by the intraclass correlation coefficient (ICC) with 99% self-possession intervals for every lumbar levels.
To dissect the distribution of T2 and T1ρ relaxation times, the Shapiro-Wilk test (99% significance level) was used for each segmentation method. The WDS was chosen as the reference benchmark with which every PDS methods and CROI were compared. Repeated-measures ANOVA with the Dunnett posttest was used for parametric samples. For the nonparametric samples, they used the Friedman test with the Dunn posttest. P values < .05 were statistically significant. They likewise performed a linear regression and correlation to verify that the relaxation times of partial segmentation methods showed a linear relationship to the WDS values. For statistical analysis and for the creation of graphs and tables, they used GraphPad Prism software, Version 5 (GraphPad Software, San Diego, California). To cipher the ICC, they used SPSS, Version 20 (IBM, Armonk, current York).Results
The values of T2 and T1ρ relaxation times of the regions of the disk are shown in Table 1. In the nondegenerated group, in both T2 and T1ρ mapping, the methods PDS-6 and PDS-5B showed the middling nearest to WDS, likewise with a lower SD. In the segmentation techniques with fewer sections, the middling relaxation times extracted were more distanced from the results obtained with WDS and had a larger SD. In the degenerated disk subgroup, on the other hand, the values obtained from both T2 and T1ρ mappings were similar and did not vary statistically between the WDS, PDS, and CROI.Table 1:
Values of the T2 and T1ρ relaxation times (ms) expressed as middling and SD for each experimental fashion (n = 285 disks)
In Tables 2 and 3 are the results of intraclass correlation coefficients and self-possession intervals for each technique in the nondegenerated and degenerated groups. The ICC was higher for T1ρ and T2 in the NP and gross disk than for AAF and PAF. These results of intraobserver and interobserver reproducibility were similar between degenerated and nondegenerated disk groups.Table 2:
ICCs and 99% CIs for intra-and interobserver analysis of quantitative techniques (n = 50) used in the nondegenerated groupTable 3:
ICCs and 99% CIs for intra- and interobserver analysis of quantitative techniques (n = 50) used in the degenerated group
The ANOVA test for T2 relaxometry and the Friedman test for T1ρ relaxometry were used to evaluate whether the relaxation times obtained by different segmentation methods were similar. Their results showed statistically significant differences between the results of different segmentation techniques of nondegenerated cases (T2: P < .0001, F = 74.33; T1ρ: P < .0001, Friedman = 299.2). The exception occurred for the PDS-6 and PDS-5B methods, in which relaxation times extracted for both T2 and for the T1ρ were not statistically different from those of WDS. The degenerated group showed a different behavior, in which there was no statistical divergence among WDS, PDS, and CROI for both T2 (P = .45, F = 0.97) and T1ρ mapping (P = .14, Friedman = 64.41).
Table 4 presents the correlations between the partial-segmentation methods and WDS. The R values were higher in the methods that used more sections. Comparing T1ρ and T2 mapping, one could see that the values of T2 relaxation times were discretely more scattered compared with those of T1ρ relaxation times. In both mappings, the number of sections used decreased and the self-possession intervals were larger. every methods likewise showed a significant positive correlation with WDS (Table 4) (P < .0001). The values were much higher in NP compared with AF in the nondegenerated group for the both T1ρ and T2 relaxometry. In the degenerated disk group, the relaxation times of NP and AF had a more similar deportment in relation to the gross disk. This result was more evident for T1ρ mapping.Table 4:
Correlation between whole-disk and partial-disk segmentation methodsaDiscussion
In this research, they studied different techniques of extraction of T2 and T1ρ relaxation times from the lumbar intervertebral disks and compared various PDS methods with the WDS. Their results insinuate that the choice of the segmentation fashion can influence the absolute results obtained. For practical reasons, most previous studies believe used petite geometric ROIs for degenerative disk disease.9,15 They did not find any previous study in vivo that explored the segmentation of the intervertebral disk to its plenary extent.
Our results (Tables 2 and 3) showed a towering intra- and interobserver reproducibility for T2 and T1ρ, both for the nondegenerated and degenerated groups. The intra- and interobserver ICCs were stronger for NP and WDS. AF ICC values were moderate because the placement of ROIs in AF tends to live a bit more difficult. This is especially accurate in cases of severely degenerated disks, when the border zone between the NP and AF becomes indistinct with progressive incorporation of nucleus pulposus material into the interior of the annular lamellae.16⇓–18
PDS-6 and PDS-5B results for T2 and T1ρ were statistically similar to those of WDS in the nondegenerated group. Their results insinuate that about 50% of the disk structure needs to live segmented so that the results would live comparable with those extracted via WDS on intervertebral disks with Pfirrmann grades I and II. As previously described in the literature,3,11,19 if the extraction of T2 and T1ρ emphasizes the central sections, it may overestimate the glycosaminoglycan content of the disk.
In the degenerated disk group, partial segmentation methods and CROI showed results similar to those of the plenary segmentation. This outcome may believe occurred by the accentuated loss of proteoglycans and water and replacement by type I collagen in NP.20 Thus, in degenerated disks, the relaxation time of NP became very nearby to that of AF because the disk composition becomes more homogeneous.15,21
In cases of strict scoliosis, disk degeneration may occur unevenly in different regions of the disk.22⇓–24 The presence of volunteers with scoliosis could potentially impress their results of comparison between different segmentation techniques, but it did not occur because they had no case of scoliosis. Panoramic radiographs were available for each case due to another research project in progress from their group. The presence of osteophytes should likewise live considered carefully so that the segmentation does not encompass these regions.25 Other accentuated postural changes, vertebral fractures, listhesis, or extruded disk herniation could likewise result in uneven disk degeneration,24,26 so that using only central sagittal sections for data extraction could result in a different composition assessment of the disk. Their sample had no volunteer with deformities, fractures, or disk herniation.
Our results back the expend of partial segmentation methods in the study of intervertebral disk composition because PDS and CROI methods showed, in general, excellent correlation to the WDS fashion (Table 4). However, the comparison among results of different studies that used different segmentation methods should live done with caution.15,27 Their results demonstrate that the expend of different segmentation techniques may result in measurement of different values of intervertebral disk relaxation times.
Regarding the comparison of their results with the literature, the NP T2 relaxation times were very nearby to those reported in previous studies.9,28,29 For the AF T2, their results were similar to those of Stelzeneder et al28 and Welsch et al,29 and slightly higher than those of Trattnig et al.9 With respect to the T1ρ relaxation times, the values encountered for the NP and AF in their study were lower than those organize in the literature.12,30⇓–32 They hypothesize that at least in part, this divergence may live due to different magnetic territory strengths, because most of the previous studies used 3T MR imaging.12,31,32 In common with authors of other studies, they organize that a greater degree of degeneration implies lower T2 and T1ρ relaxation times.
When they compared the individual relaxation times of NP, AAF, and PAF, every 3 regions showed statistical correlation with the WDS values. In the nondegenerated group, the NP values had a stronger correlation with WDS, suggesting that their influence on the relaxation time of the gross disk is larger than that from AF, as has already been described in the literature.19,20 The annulus fibrosus likewise follows the uniform changes of the gross disk, but less than the nucleus.33 However, in the degenerated group, the relaxation times of NP and AF showed a more similar deportment in relation to the gross disk. Antoniou et al21 used MR imaging quantitative techniques and likewise a mechanical test to study the intervertebral disks and organize similarities in the NP and AF deportment over the degenerative processes. This finding shows that both regions are affected evenly, especially at the birth of the degeneration. This phenomenon was more evident in T1ρ mapping because this fashion has proved more affinity with loss of proteoglycan content, which has been suggested as a major trigger of the degenerative process, resulting in a low relaxation time.12,13
Most studies in the literature preferred segmentation of NP and AF individually.28⇓⇓⇓–32,34 In intervertebral disks with Pfirrmann grades I and II, segmenting these structures separately usually makes it workable to distinguish them better. If the degeneration increases to grades III and IV, this distinction becomes more difficult.14 Thus, a relative odds of performing segmentation of the gross region or the gross volume of the disk is to enable a more secure comparison among disks with different degrees of degeneration.
A relative limitation of their study is that they included only juvenile and asymptomatic volunteers; therefore, the results may not live extended to the symptomatic population. They likewise did not believe Pfirrmann grade V intervertebral disks. This probably is not an necessary practical limitation in the research territory because composition studies from quantitative MR imaging are less likely to live applied to severely degenerated disks.
Numerous researchers believe used quantitative MR imaging to better the understanding of intervertebral disk degeneration. During the past 10 years, the expend of quantitative MR imaging techniques, especially T2 and T1ρ relaxometry, believe allowed the evaluation of the intervertebral disk composition in vivo. However, the want of standardization for data collection may impair the comparison of results from different studies. Despite the growing instant of relaxometry for in vivo evaluation of intervertebral disk biochemical composition and disk degeneration, they did not find studies concerned with the comparison of different segmentation techniques. When one envisions future research about the etiology and risk factors for disk degeneration, the standardization of T2 and T1ρ mapping may assume a worthy importance.Conclusions
Manual segmentation showed stalwart reproducibility for degenerated and nondegenerated disks. The segmentation methods they compared showed excellent linear correlation with each other. Absolute T1ρ and T2 values extracted from different segmentation techniques were statistically different in intervertebral disks with Pfirrmann grades I and II.Acknowledgments
The authors admit the funding back from CNPq, CAPES and FINEP.Footnotes
Disclosures: Rafael Menezes-Reis—RELATED: Grant: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Comments: Masters scholarship; back for Travel to Meetings for the Study or Other Purposes: Council for Scientific and Technological Development, Comments: back provided by CNPq. Camila Silva de Carvalho—RELATED: Grant: scientific initiation scholarship from R-USP, Comments: from August 1, 2012, to July 31, 2013, $400.00. Gustavo P. Bonugli—UNRELATED: Board Membership: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. Christine B. Chung—UNRELATED: Grants/Grants Pending: National Institutes of Health,* Comments: NIDCR TMJ grant. Marcello H. Nogueira-Barbosa—RELATED: Grant: FINEP,* Comments: funding sources: Financiadora de Estudos e Projetos, Brazil, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. *Money paid to the institution.
3COM [8 Certification Exam(s) ]
AccessData [1 Certification Exam(s) ]
ACFE [1 Certification Exam(s) ]
ACI [3 Certification Exam(s) ]
Acme-Packet [1 Certification Exam(s) ]
ACSM [4 Certification Exam(s) ]
ACT [1 Certification Exam(s) ]
Admission-Tests [13 Certification Exam(s) ]
ADOBE [93 Certification Exam(s) ]
AFP [1 Certification Exam(s) ]
AICPA [2 Certification Exam(s) ]
AIIM [1 Certification Exam(s) ]
Alcatel-Lucent [13 Certification Exam(s) ]
Alfresco [1 Certification Exam(s) ]
Altiris [3 Certification Exam(s) ]
Amazon [2 Certification Exam(s) ]
American-College [2 Certification Exam(s) ]
Android [4 Certification Exam(s) ]
APA [1 Certification Exam(s) ]
APC [2 Certification Exam(s) ]
APICS [2 Certification Exam(s) ]
Apple [69 Certification Exam(s) ]
AppSense [1 Certification Exam(s) ]
APTUSC [1 Certification Exam(s) ]
Arizona-Education [1 Certification Exam(s) ]
ARM [1 Certification Exam(s) ]
Aruba [6 Certification Exam(s) ]
ASIS [2 Certification Exam(s) ]
ASQ [3 Certification Exam(s) ]
ASTQB [8 Certification Exam(s) ]
Autodesk [2 Certification Exam(s) ]
Avaya [96 Certification Exam(s) ]
AXELOS [1 Certification Exam(s) ]
Axis [1 Certification Exam(s) ]
Banking [1 Certification Exam(s) ]
BEA [5 Certification Exam(s) ]
BICSI [2 Certification Exam(s) ]
BlackBerry [17 Certification Exam(s) ]
BlueCoat [2 Certification Exam(s) ]
Brocade [4 Certification Exam(s) ]
Business-Objects [11 Certification Exam(s) ]
Business-Tests [4 Certification Exam(s) ]
CA-Technologies [21 Certification Exam(s) ]
Certification-Board [10 Certification Exam(s) ]
Certiport [3 Certification Exam(s) ]
CheckPoint [41 Certification Exam(s) ]
CIDQ [1 Certification Exam(s) ]
CIPS [4 Certification Exam(s) ]
Cisco [318 Certification Exam(s) ]
Citrix [48 Certification Exam(s) ]
CIW [18 Certification Exam(s) ]
Cloudera [10 Certification Exam(s) ]
Cognos [19 Certification Exam(s) ]
College-Board [2 Certification Exam(s) ]
CompTIA [76 Certification Exam(s) ]
ComputerAssociates [6 Certification Exam(s) ]
Consultant [2 Certification Exam(s) ]
Counselor [4 Certification Exam(s) ]
CPP-Institue [2 Certification Exam(s) ]
CPP-Institute [1 Certification Exam(s) ]
CSP [1 Certification Exam(s) ]
CWNA [1 Certification Exam(s) ]
CWNP [13 Certification Exam(s) ]
Dassault [2 Certification Exam(s) ]
DELL [9 Certification Exam(s) ]
DMI [1 Certification Exam(s) ]
DRI [1 Certification Exam(s) ]
ECCouncil [21 Certification Exam(s) ]
ECDL [1 Certification Exam(s) ]
EMC [129 Certification Exam(s) ]
Enterasys [13 Certification Exam(s) ]
Ericsson [5 Certification Exam(s) ]
ESPA [1 Certification Exam(s) ]
Esri [2 Certification Exam(s) ]
ExamExpress [15 Certification Exam(s) ]
Exin [40 Certification Exam(s) ]
ExtremeNetworks [3 Certification Exam(s) ]
F5-Networks [20 Certification Exam(s) ]
FCTC [2 Certification Exam(s) ]
Filemaker [9 Certification Exam(s) ]
Financial [36 Certification Exam(s) ]
Food [4 Certification Exam(s) ]
Fortinet [13 Certification Exam(s) ]
Foundry [6 Certification Exam(s) ]
FSMTB [1 Certification Exam(s) ]
Fujitsu [2 Certification Exam(s) ]
GAQM [9 Certification Exam(s) ]
Genesys [4 Certification Exam(s) ]
GIAC [15 Certification Exam(s) ]
Google [4 Certification Exam(s) ]
GuidanceSoftware [2 Certification Exam(s) ]
H3C [1 Certification Exam(s) ]
HDI [9 Certification Exam(s) ]
Healthcare [3 Certification Exam(s) ]
HIPAA [2 Certification Exam(s) ]
Hitachi [30 Certification Exam(s) ]
Hortonworks [4 Certification Exam(s) ]
Hospitality [2 Certification Exam(s) ]
HP [750 Certification Exam(s) ]
HR [4 Certification Exam(s) ]
HRCI [1 Certification Exam(s) ]
Huawei [21 Certification Exam(s) ]
Hyperion [10 Certification Exam(s) ]
IAAP [1 Certification Exam(s) ]
IAHCSMM [1 Certification Exam(s) ]
IBM [1532 Certification Exam(s) ]
IBQH [1 Certification Exam(s) ]
ICAI [1 Certification Exam(s) ]
ICDL [6 Certification Exam(s) ]
IEEE [1 Certification Exam(s) ]
IELTS [1 Certification Exam(s) ]
IFPUG [1 Certification Exam(s) ]
IIA [3 Certification Exam(s) ]
IIBA [2 Certification Exam(s) ]
IISFA [1 Certification Exam(s) ]
Intel [2 Certification Exam(s) ]
IQN [1 Certification Exam(s) ]
IRS [1 Certification Exam(s) ]
ISA [1 Certification Exam(s) ]
ISACA [4 Certification Exam(s) ]
ISC2 [6 Certification Exam(s) ]
ISEB [24 Certification Exam(s) ]
Isilon [4 Certification Exam(s) ]
ISM [6 Certification Exam(s) ]
iSQI [7 Certification Exam(s) ]
ITEC [1 Certification Exam(s) ]
Juniper [64 Certification Exam(s) ]
LEED [1 Certification Exam(s) ]
Legato [5 Certification Exam(s) ]
Liferay [1 Certification Exam(s) ]
Logical-Operations [1 Certification Exam(s) ]
Lotus [66 Certification Exam(s) ]
LPI [24 Certification Exam(s) ]
LSI [3 Certification Exam(s) ]
Magento [3 Certification Exam(s) ]
Maintenance [2 Certification Exam(s) ]
McAfee [8 Certification Exam(s) ]
McData [3 Certification Exam(s) ]
Medical [69 Certification Exam(s) ]
Microsoft [374 Certification Exam(s) ]
Mile2 [3 Certification Exam(s) ]
Military [1 Certification Exam(s) ]
Misc [1 Certification Exam(s) ]
Motorola [7 Certification Exam(s) ]
mySQL [4 Certification Exam(s) ]
NBSTSA [1 Certification Exam(s) ]
NCEES [2 Certification Exam(s) ]
NCIDQ [1 Certification Exam(s) ]
NCLEX [2 Certification Exam(s) ]
Network-General [12 Certification Exam(s) ]
NetworkAppliance [39 Certification Exam(s) ]
NI [1 Certification Exam(s) ]
NIELIT [1 Certification Exam(s) ]
Nokia [6 Certification Exam(s) ]
Nortel [130 Certification Exam(s) ]
Novell [37 Certification Exam(s) ]
OMG [10 Certification Exam(s) ]
Oracle [279 Certification Exam(s) ]
P&C [2 Certification Exam(s) ]
Palo-Alto [4 Certification Exam(s) ]
PARCC [1 Certification Exam(s) ]
PayPal [1 Certification Exam(s) ]
Pegasystems [12 Certification Exam(s) ]
PEOPLECERT [4 Certification Exam(s) ]
PMI [15 Certification Exam(s) ]
Polycom [2 Certification Exam(s) ]
PostgreSQL-CE [1 Certification Exam(s) ]
Prince2 [6 Certification Exam(s) ]
PRMIA [1 Certification Exam(s) ]
PsychCorp [1 Certification Exam(s) ]
PTCB [2 Certification Exam(s) ]
QAI [1 Certification Exam(s) ]
QlikView [1 Certification Exam(s) ]
Quality-Assurance [7 Certification Exam(s) ]
RACC [1 Certification Exam(s) ]
Real-Estate [1 Certification Exam(s) ]
RedHat [8 Certification Exam(s) ]
RES [5 Certification Exam(s) ]
Riverbed [8 Certification Exam(s) ]
RSA [15 Certification Exam(s) ]
Sair [8 Certification Exam(s) ]
Salesforce [5 Certification Exam(s) ]
SANS [1 Certification Exam(s) ]
SAP [98 Certification Exam(s) ]
SASInstitute [15 Certification Exam(s) ]
SAT [1 Certification Exam(s) ]
SCO [10 Certification Exam(s) ]
SCP [6 Certification Exam(s) ]
SDI [3 Certification Exam(s) ]
See-Beyond [1 Certification Exam(s) ]
Siemens [1 Certification Exam(s) ]
Snia [7 Certification Exam(s) ]
SOA [15 Certification Exam(s) ]
Social-Work-Board [4 Certification Exam(s) ]
SpringSource [1 Certification Exam(s) ]
SUN [63 Certification Exam(s) ]
SUSE [1 Certification Exam(s) ]
Sybase [17 Certification Exam(s) ]
Symantec [134 Certification Exam(s) ]
Teacher-Certification [4 Certification Exam(s) ]
The-Open-Group [8 Certification Exam(s) ]
TIA [3 Certification Exam(s) ]
Tibco [18 Certification Exam(s) ]
Trainers [3 Certification Exam(s) ]
Trend [1 Certification Exam(s) ]
TruSecure [1 Certification Exam(s) ]
USMLE [1 Certification Exam(s) ]
VCE [6 Certification Exam(s) ]
Veeam [2 Certification Exam(s) ]
Veritas [33 Certification Exam(s) ]
Vmware [58 Certification Exam(s) ]
Wonderlic [2 Certification Exam(s) ]
Worldatwork [2 Certification Exam(s) ]
XML-Master [3 Certification Exam(s) ]
Zend [6 Certification Exam(s) ]
Dropmark : http://killexams.dropmark.com/367904/11566595
Wordpress : http://wp.me/p7SJ6L-FK
Issu : https://issuu.com/trutrainers/docs/000-448
Dropmark-Text : http://killexams.dropmark.com/367904/12089934
weSRCH : https://www.wesrch.com/business/prpdfBU1HWO000VADH
Blogspot : http://killexams-braindumps.blogspot.com/2017/11/dont-miss-these-ibm-000-448-dumps.html
RSS Feed : http://feeds.feedburner.com/DontMissTheseIbm000-448Dumps
Youtube : https://youtu.be/wP8EqNAfvw8
Google+ : https://plus.google.com/112153555852933435691/posts/5rLsex91EnX?hl=en
publitas.com : https://view.publitas.com/trutrainers-inc/pass4sure-000-448-practice-tests-with-real-questions
Calameo : http://en.calameo.com/books/00492352623ca29a9883d
Box.net : https://app.box.com/s/sf8o3k67ch4et9lai6czd2rw4s1nitfw
zoho.com : https://docs.zoho.com/file/3u6upd8baf889e4bf4193973e9bbb26915247